BACKGROUND: Given the increasing incidence of measles, the aim was to assess the seroprevalence of measles immunity among employees of a Czech tertiary care hospital and to assess their willingness to revaccination. METHODS: 3027 hospital employees (2421 females, 606 males) underwent a serological analysis of their measles antibody levels with an option of revaccination in case of an insufficient level. RESULTS: The median age of participants was 42 years. Seropositivity was noted in 54% of the participants, with the antibody values higher in the oldest study participants and with a decrease around the birth year 1968. Logistic regression analysis confirmed a significant relationship of seropositivity with age (odds ratio 0.97, p < 0.005). Out of the seronegative, 80.9% individuals got revaccinated. CONCLUSIONS: 46% of the participants did not reach a sufficient antibody level set by the assay's manufacturer. Although the routine vaccination system is well established it may be ineffective.

Department of Occupational Medicine University Hospital Olomouc and Faculty of Medicine and Dentistry Palacký University Olomouc 1 P Pavlova 185 6 779 00 Olomouc Czech Republic

Department of Public Health Faculty of Medicine and Dentistry Palacký University Olomouc Hněvotínská 976 3 775 15 Olomouc Czech Republic

Institute of Biophysics and Informatics 1st Faculty of Medicine Charles University Salmovská 1 120 00 Praha 2 Czech Republic

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$a Štěpánek, Ladislav $u Department of Occupational Medicine, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 185/6, 779 00 Olomouc, Czech Republic. Electronic address: ladislav.stepanek@fnol.cz

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$a Measles immunity in a Czech tertiary care hospital / $c L. Štěpánek, M. Nakládalová, A. Boriková, D. Horáková, L. Štěpánek

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$a BACKGROUND: Given the increasing incidence of measles, the aim was to assess the seroprevalence of measles immunity among employees of a Czech tertiary care hospital and to assess their willingness to revaccination. METHODS: 3027 hospital employees (2421 females, 606 males) underwent a serological analysis of their measles antibody levels with an option of revaccination in case of an insufficient level. RESULTS: The median age of participants was 42 years. Seropositivity was noted in 54% of the participants, with the antibody values higher in the oldest study participants and with a decrease around the birth year 1968. Logistic regression analysis confirmed a significant relationship of seropositivity with age (odds ratio 0.97, p < 0.005). Out of the seronegative, 80.9% individuals got revaccinated. CONCLUSIONS: 46% of the participants did not reach a sufficient antibody level set by the assay's manufacturer. Although the routine vaccination system is well established it may be ineffective.

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$a Nakládalová, Marie $u Department of Occupational Medicine, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 185/6, 779 00 Olomouc, Czech Republic. Electronic address: marie.nakladalova@fnol.cz

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$a Boriková, Alena $u Department of Occupational Medicine, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 185/6, 779 00 Olomouc, Czech Republic. Electronic address: alena.borikova@fnol.cz

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$a Horáková, Dagmar $u Department of Public Health, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hněvotínská 976/3, 775 15 Olomouc, Czech Republic. Electronic address: dagmar.horakova@upol.cz

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$a Štěpánek, Lubomír $u Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Salmovská 1, 120 00 Praha 2, Czech Republic. Electronic address: Lubomir.Stepanek@lf1.cuni.cz

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