-
Je něco špatně v tomto záznamu ?
Decellularized xenogeneic scaffolds in transplantation and tissue engineering: Immunogenicity versus positive cell stimulation
MS. Massaro, R. Pálek, J. Rosendorf, L. Červenková, V. Liška, V. Moulisová
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, přehledy
- MeSH
- biokompatibilní materiály MeSH
- extracelulární matrix MeSH
- heterografty MeSH
- tkáňové inženýrství * MeSH
- tkáňové podpůrné struktury * MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Seriously compromised function of some organs can only be restored by transplantation. Due to the shortage of human donors, the need to find another source of organs is of primary importance. Decellularized scaffolds of non-human origin are being studied as highly potential biomaterials for tissue engineering. Their biological nature and thus the ability to provide a naturally-derived environment for human cells to adhere and grow highlights their great advantage in comparison to synthetic scaffolds. Nevertheless, since every biomaterial implanted in the body generates immune reaction, studying the interaction of the scaffold with the surrounding tissues is necessary. This review aims to summarize current knowledge on the immunogenicity of semi-xenografts involved in transplantation. Moreover, positive aspects of the interaction between xenogeneic scaffold and human cells are discussed, focusing on specific roles of proteins associated with extracellular matrix in cell adhesion and signalling.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21025248
- 003
- CZ-PrNML
- 005
- 20211026134005.0
- 007
- ta
- 008
- 211013s2021 ne f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.msec.2021.112203 $2 doi
- 035 __
- $a (PubMed)34225855
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Massaro, Maria Stefania $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic
- 245 10
- $a Decellularized xenogeneic scaffolds in transplantation and tissue engineering: Immunogenicity versus positive cell stimulation / $c MS. Massaro, R. Pálek, J. Rosendorf, L. Červenková, V. Liška, V. Moulisová
- 520 9_
- $a Seriously compromised function of some organs can only be restored by transplantation. Due to the shortage of human donors, the need to find another source of organs is of primary importance. Decellularized scaffolds of non-human origin are being studied as highly potential biomaterials for tissue engineering. Their biological nature and thus the ability to provide a naturally-derived environment for human cells to adhere and grow highlights their great advantage in comparison to synthetic scaffolds. Nevertheless, since every biomaterial implanted in the body generates immune reaction, studying the interaction of the scaffold with the surrounding tissues is necessary. This review aims to summarize current knowledge on the immunogenicity of semi-xenografts involved in transplantation. Moreover, positive aspects of the interaction between xenogeneic scaffold and human cells are discussed, focusing on specific roles of proteins associated with extracellular matrix in cell adhesion and signalling.
- 650 _2
- $a biokompatibilní materiály $7 D001672
- 650 _2
- $a extracelulární matrix $7 D005109
- 650 _2
- $a heterografty $7 D064593
- 650 12
- $a tkáňové inženýrství $7 D023822
- 650 12
- $a tkáňové podpůrné struktury $7 D054457
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Pálek, Richard $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic; Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 80, 32300 Pilsen, Czech Republic
- 700 1_
- $a Rosendorf, Jáchym $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic; Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 80, 32300 Pilsen, Czech Republic
- 700 1_
- $a Červenková, Lenka $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic; Department of Pathology, Third Faculty of Medicine, Charles University, Ruska 87, 100 00 Prague 10, Czech Republic
- 700 1_
- $a Liška, Václav $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic; Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 80, 32300 Pilsen, Czech Republic
- 700 1_
- $a Moulisová, Vladimíra $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 32300 Pilsen, Czech Republic. Electronic address: vladimira.moulisova@lfp.cuni.cz
- 773 0_
- $w MED00184559 $t Materials science & engineering. C, Materials for biological applications $x 1873-0191 $g Roč. 127, č. - (2021), s. 112203
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/34225855 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20211013 $b ABA008
- 991 __
- $a 20211026134011 $b ABA008
- 999 __
- $a ok $b bmc $g 1714346 $s 1145755
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 127 $c - $d 112203 $e 20210521 $i 1873-0191 $m Materials science & engineering. C, Materials for biological applications $n Mater Sci Eng C Mater Biol Appl $x MED00184559
- LZP __
- $a Pubmed-20211013
