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Fumonisin B1: Mechanisms of toxicity and biological detoxification progress in animals
J. Chen, Z. Wei, Y. Wang, M. Long, W. Wu, K. Kuca
Food and chemical toxicology.
2021 ;
149 (-) :
111977.
[pub] 20210109
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, přehledy
Perzistentní odkaz
https://www.medvik.cz/link/bmc21026011
- MeSH
- apoptóza účinky léků MeSH
- fumonisiny chemie metabolismus toxicita MeSH
- Fusarium metabolismus MeSH
- kontaminace potravin * MeSH
- krmivo pro zvířata analýza MeSH
- oxidační stres účinky léků MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Fumonisin B1 (FB1) is a toxic secondary metabolite produced by the Fusarium molds that can contaminate food and feed. It has been found that FB1 can cause systemic toxicity, including neurotoxicity, hepatotoxicity, nephrotoxicity and mammalian cytotoxicity. This review addresses the toxicity studies carried out on FB1 and outlines the probable mechanisms underlying its immunotoxicity, reproductive toxicity, joint toxicity, apoptosis, and autophagy. In the present work, the research progress of FB1 detoxification in recent years is reviewed, which provides reference for controlling and reducing the toxicity of FB1.
Citace poskytuje Crossref.org
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- $a Wu, Wenda $u MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003, Hradec Kralove, Czech Republic. Electronic address: wuwenda@njau.edu.cn
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