• Je něco špatně v tomto záznamu ?

Effects of concentrated growth factor and nanofat on aging skin of nude mice induced by D-galactose

W. Sun, T. Li, H. Yao, L. Kang, F. Dong

. 2021 ; 70 (3) : 425-435. [pub] 20210512

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc22000848

This investigation studied the effect of concentrated growth factor and nanofat on aging skin of nude mice induced by D-galactose. BALB/c mice were randomly divided into five groups: 5 mice in the control group were fed normally without any intervention, 9 mice were treated with concentrated growth factor (CGF), 9 mice were treated with nanofat (NF), 9 mice were treated with CGF+NF, and 9 mice in the model group (no treatment after subcutaneous injection of D-galactose). Relevant indicators are measured and recorded. In skin and serum, SOD and GSH content in the model group were significantly lower than those in other groups (P<0.05), and the MDA of the three treatment groups was significantly lower than that of the model group (P<0.05). Compared with the control group, the contents of total collagen, type I collagen and type III collagen in the NF group and model group were decreased in different degrees (P<0.05); the contents of elastin and elastic fiber in the skin of nude mice in the model group and NF group were significantly decreased. Compared with the model group, he number of CD31 and VEGF in the treatment group was significantly increased (P<0.01); the skin AGE content of three treatment groups was significantly lower (P<0.05). These findings suggest that concentrated growth factor and nanofat may have a significant effect on delaying aging skin induced by D-galactose in nude mice.

Citace poskytuje Crossref.org

Bibliografie atd.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc22000848
003      
CZ-PrNML
005      
20220202102440.0
007      
ta
008      
220106s2021 xr d f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.934640 $2 doi
035    __
$a (PubMed)33982585
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Sun, W. $u Department of Esthetic Surgery, Beijing Evercare Medical Beauty Hospital, Beijing, China
245    10
$a Effects of concentrated growth factor and nanofat on aging skin of nude mice induced by D-galactose / $c W. Sun, T. Li, H. Yao, L. Kang, F. Dong
504    __
$a Literatura
520    9_
$a This investigation studied the effect of concentrated growth factor and nanofat on aging skin of nude mice induced by D-galactose. BALB/c mice were randomly divided into five groups: 5 mice in the control group were fed normally without any intervention, 9 mice were treated with concentrated growth factor (CGF), 9 mice were treated with nanofat (NF), 9 mice were treated with CGF+NF, and 9 mice in the model group (no treatment after subcutaneous injection of D-galactose). Relevant indicators are measured and recorded. In skin and serum, SOD and GSH content in the model group were significantly lower than those in other groups (P<0.05), and the MDA of the three treatment groups was significantly lower than that of the model group (P<0.05). Compared with the control group, the contents of total collagen, type I collagen and type III collagen in the NF group and model group were decreased in different degrees (P<0.05); the contents of elastin and elastic fiber in the skin of nude mice in the model group and NF group were significantly decreased. Compared with the model group, he number of CD31 and VEGF in the treatment group was significantly increased (P<0.01); the skin AGE content of three treatment groups was significantly lower (P<0.05). These findings suggest that concentrated growth factor and nanofat may have a significant effect on delaying aging skin induced by D-galactose in nude mice.
650    _2
$a tuková tkáň $x transplantace $7 D000273
650    _2
$a zvířata $7 D000818
650    _2
$a kolagen $x metabolismus $7 D003094
650    _2
$a elastin $x metabolismus $7 D004549
650    _2
$a galaktosa $x farmakologie $7 D005690
650    _2
$a glutathion $x metabolismus $7 D005978
650    _2
$a mezibuněčné signální peptidy a proteiny $x farmakologie $7 D036341
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a myši $7 D051379
650    _2
$a myši inbrední BALB C $7 D008807
650    _2
$a myši nahé $7 D008819
650    _2
$a antigeny CD31 $x metabolismus $7 D019408
650    _2
$a stárnutí kůže $x účinky léků $7 D015595
650    _2
$a superoxiddismutasa $x metabolismus $7 D013482
650    _2
$a vaskulární endoteliální růstový faktor A $x metabolismus $7 D042461
655    _2
$a časopisecké články $7 D016428
700    1_
$a Li, T. $u Department of Esthetic Surgery, Beijing Evercare Medical Beauty Hospital, Beijing, China
700    1_
$a Yao, H. $u Department of Esthetic Surgery, Beijing Evercare Medical Beauty Hospital, Beijing, China
700    1_
$a Kang, L. $u Department of Pathology, Hebei General Hospital, Hebei, China
700    1_
$a Dong, F. $u Department of Oral and Maxillofacial Surgery, Stomatology Hospital of Hebei Medical University, Shijiazhuang, Hebei, China $u Hebei Key Laboratory of Oral Medicine, Shijiazhuang, Hebei, China
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 70, č. 3 (2021), s. 425-435
856    41
$u https://pubmed.ncbi.nlm.nih.gov/33982585 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y p $z 0
990    __
$a 20220106 $b ABA008
991    __
$a 20220202102429 $b ABA008
999    __
$a ok $b bmc $g 1755679 $s 1151994
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 70 $c 3 $d 425-435 $e 20210512 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
LZP    __
$b NLK118 $a Pubmed-20220106

Najít záznam

Citační ukazatele

Možnosti archivace