-
Je něco špatně v tomto záznamu ?
Developments in the Histopathological Classification of ANCA-Associated Glomerulonephritis
EE. van Daalen, MAC. Wester Trejo, A. Göçeroğlu, F. Ferrario, K. Joh, LH. Noël, Y. Ogawa, S. Wilhelmus, MJ. Ball, E. Honsova, Z. Hruskova, R. Kain, T. Kimura, M. Kollar, A. Kronbichler, K. Lindhard, X. Puéchal, S. Salvatore, W. Szpirt, H....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, metaanalýza, multicentrická studie, práce podpořená grantem, přehledy, validační studie
NLK
Free Medical Journals
od 2006 do Před 1 rokem
PubMed Central
od 2008 do Před 1 rokem
Europe PubMed Central
od 2008 do Před 1 rokem
Open Access Digital Library
od 2006-01-01
PubMed
32723805
DOI
10.2215/cjn.14561119
Knihovny.cz E-zdroje
- MeSH
- biopsie MeSH
- časové faktory MeSH
- glomerulonefritida klasifikace komplikace imunologie patologie MeSH
- ledviny imunologie patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- prediktivní hodnota testů MeSH
- prognóza MeSH
- progrese nemoci MeSH
- protilátky proti cytoplazmě neutrofilů imunologie MeSH
- renální insuficience diagnóza etiologie MeSH
- reprodukovatelnost výsledků MeSH
- retrospektivní studie MeSH
- rizikové faktory MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- validační studie MeSH
BACKGROUND AND OBJECTIVES: The histopathologic classification for ANCA-associated GN distinguishes four classes on the basis of patterns of injury. In the original validation study, these classes were ordered by severity of kidney function loss as follows: focal, crescentic, mixed, and sclerotic. Subsequent validation studies disagreed on outcomes in the crescentic and mixed classes. This study, driven by the original investigators, provides several analyses in order to determine the current position of the histopathologic classification of ANCA-associated GN. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A validation study was performed with newly collected data from 145 patients from ten centers worldwide, including an analysis of interobserver agreement on the histopathologic evaluation of the kidney biopsies. This study also included a meta-analysis on previous validation studies and a validation of the recently proposed ANCA kidney risk score. RESULTS: The validation study showed that kidney failure at 10-year follow-up was significantly different between the histopathologic classes (P<0.001). Kidney failure at 10-year follow-up was 14% in the crescentic class versus 20% in the mixed class (P=0.98). In the meta-analysis, no significant difference in kidney failure was also observed when crescentic class was compared with mixed class (relative risk, 1.15; 95% confidence interval, 0.94 to 1.41). When we applied the ANCA kidney risk score to our cohort, kidney survival at 3 years was 100%, 96%, and 77% in the low-, medium-, and high-risk groups, respectively (P<0.001). These survival percentages are higher compared with the percentages in the original study. CONCLUSIONS: The crescentic and mixed classes seem to have a similar prognosis, also after adjusting for differences in patient populations, treatment, and interobserver agreement. However, at this stage, we are not inclined to merge the crescentic and mixed classes because the reported confidence intervals do not exclude important differences in prognosis and because an important histopathologic distinction would be lost.
Clinical Institute of Pathology Medical University of Vienna Vienna Austria
Department of Clinical Epidemiology Leiden University Medical Center Leiden The Netherlands
Department of Internal Medicine 4 Medical University Innsbruck Innsbruck Austria
Department of Internal Medicine St Antoniusziekenhuis Nieuwegein The Netherlands
Department of Nephrology Japan Community Healthcare Organization Sendai Hospital Sendai Japan
Department of Nephrology Leiden University Medical Center Leiden The Netherlands
Department of Nephrology Meander Medical Center Amersfoort The Netherlands
Department of Nephrology Rigshospitalet University of Copenhagen Copenhagen Denmark
Department of Nephrology Teine Keijinkai Hospital Sapporo Japan
Department of Pathology Institute for Clinical and Experimental Medicine Prague Czech Republic
Department of Pathology Leiden University Medical Center Leiden The Netherlands
Department of Pathology Necker Hospital René Descartes University Paris France
Department of Pathology The Jikei University School of Medicine Tokyo Japan
Department of Pathology Weill Cornell Medical College New York New York
Department of Rheumatology Leiden University Medical Center Leiden The Netherlands
Hokkaido Renal Pathology Center Sapporo Japan
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22004868
- 003
- CZ-PrNML
- 005
- 20220127144857.0
- 007
- ta
- 008
- 220113s2020 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.2215/CJN.14561119 $2 doi
- 035 __
- $a (PubMed)32723805
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a van Daalen, Emma E $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands emmavd@hotmail.com
- 245 10
- $a Developments in the Histopathological Classification of ANCA-Associated Glomerulonephritis / $c EE. van Daalen, MAC. Wester Trejo, A. Göçeroğlu, F. Ferrario, K. Joh, LH. Noël, Y. Ogawa, S. Wilhelmus, MJ. Ball, E. Honsova, Z. Hruskova, R. Kain, T. Kimura, M. Kollar, A. Kronbichler, K. Lindhard, X. Puéchal, S. Salvatore, W. Szpirt, H. Takizawa, V. Tesar, AE. Berden, OM. Dekkers, EC. Hagen, J. Oosting, C. Rahmattulla, R. Wolterbeek, WJ. Bos, JA. Bruijn, IM. Bajema
- 520 9_
- $a BACKGROUND AND OBJECTIVES: The histopathologic classification for ANCA-associated GN distinguishes four classes on the basis of patterns of injury. In the original validation study, these classes were ordered by severity of kidney function loss as follows: focal, crescentic, mixed, and sclerotic. Subsequent validation studies disagreed on outcomes in the crescentic and mixed classes. This study, driven by the original investigators, provides several analyses in order to determine the current position of the histopathologic classification of ANCA-associated GN. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A validation study was performed with newly collected data from 145 patients from ten centers worldwide, including an analysis of interobserver agreement on the histopathologic evaluation of the kidney biopsies. This study also included a meta-analysis on previous validation studies and a validation of the recently proposed ANCA kidney risk score. RESULTS: The validation study showed that kidney failure at 10-year follow-up was significantly different between the histopathologic classes (P<0.001). Kidney failure at 10-year follow-up was 14% in the crescentic class versus 20% in the mixed class (P=0.98). In the meta-analysis, no significant difference in kidney failure was also observed when crescentic class was compared with mixed class (relative risk, 1.15; 95% confidence interval, 0.94 to 1.41). When we applied the ANCA kidney risk score to our cohort, kidney survival at 3 years was 100%, 96%, and 77% in the low-, medium-, and high-risk groups, respectively (P<0.001). These survival percentages are higher compared with the percentages in the original study. CONCLUSIONS: The crescentic and mixed classes seem to have a similar prognosis, also after adjusting for differences in patient populations, treatment, and interobserver agreement. However, at this stage, we are not inclined to merge the crescentic and mixed classes because the reported confidence intervals do not exclude important differences in prognosis and because an important histopathologic distinction would be lost.
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a protilátky proti cytoplazmě neutrofilů $x imunologie $7 D019268
- 650 _2
- $a biopsie $7 D001706
- 650 _2
- $a progrese nemoci $7 D018450
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a glomerulonefritida $x klasifikace $x komplikace $x imunologie $x patologie $7 D005921
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a ledviny $x imunologie $x patologie $7 D007668
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a prediktivní hodnota testů $7 D011237
- 650 _2
- $a prognóza $7 D011379
- 650 _2
- $a renální insuficience $x diagnóza $x etiologie $7 D051437
- 650 _2
- $a reprodukovatelnost výsledků $7 D015203
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a rizikové faktory $7 D012307
- 650 _2
- $a časové faktory $7 D013997
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a metaanalýza $7 D017418
- 655 _2
- $a multicentrická studie $7 D016448
- 655 _2
- $a práce podpořená grantem $7 D013485
- 655 _2
- $a přehledy $7 D016454
- 655 _2
- $a validační studie $7 D023361
- 700 1_
- $a Wester Trejo, Maria A C $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Göçeroğlu, Arda $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Ferrario, Franco $u Nephropathology Center, San Gerardo Hospital, Monza, Italy
- 700 1_
- $a Joh, Kensuke $u Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan
- 700 1_
- $a Noël, Laure-Hélène $u Department of Pathology, Necker Hospital, René Descartes University, Paris, France
- 700 1_
- $a Ogawa, Yayoi $u Hokkaido Renal Pathology Center, Sapporo, Japan
- 700 1_
- $a Wilhelmus, Suzanne $u Pathology Laboratory Pathan, Rotterdam, The Netherlands
- 700 1_
- $a Ball, Miriam J $u Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
- 700 1_
- $a Honsova, Eva $u Department of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
- 700 1_
- $a Hruskova, Zdenka $u Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
- 700 1_
- $a Kain, Renate $u Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
- 700 1_
- $a Kimura, Tomoyoshi $u Department of Nephrology, Japan Community Healthcare Organization, Sendai Hospital, Sendai, Japan
- 700 1_
- $a Kollar, Marek $u Department of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
- 700 1_
- $a Kronbichler, Andreas $u Department of Internal Medicine IV (Nephrology and Hypertension), Medical University Innsbruck, Innsbruck, Austria
- 700 1_
- $a Lindhard, Kristine $u Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Puéchal, Xavier $u Department of Internal Medicine, National Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France
- 700 1_
- $a Salvatore, Steven $u Department of Pathology, Weill Cornell Medical College, New York, New York
- 700 1_
- $a Szpirt, Wladimir $u Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Takizawa, Hideki $u Department of Nephrology, Teine Keijinkai Hospital, Sapporo, Japan
- 700 1_
- $a Tesar, Vladimir $u Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
- 700 1_
- $a Berden, Annelies E $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands $u Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Dekkers, Olaf M $u Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Hagen, E Christiaan $u Department of Nephrology, Meander Medical Center, Amersfoort, The Netherlands
- 700 1_
- $a Oosting, Jan $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Rahmattulla, Chinar $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Wolterbeek, Ron $u Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Bos, Willem Jan $u Department of Internal Medicine, St. Antoniusziekenhuis, Nieuwegein, The Netherlands $u Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Bruijn, Jan A $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 700 1_
- $a Bajema, Ingeborg M $u Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
- 773 0_
- $w MED00156165 $t Clinical journal of the American Society of Nephrology : CJASN $x 1555-905X $g Roč. 15, č. 8 (2020), s. 1103-1111
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/32723805 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20220113 $b ABA008
- 991 __
- $a 20220127144854 $b ABA008
- 999 __
- $a ok $b bmc $g 1752163 $s 1156017
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 15 $c 8 $d 1103-1111 $e 20200728 $i 1555-905X $m Clinical journal of the American Society of Nephrology $n Clin J Am Soc Nephrol $x MED00156165
- LZP __
- $a Pubmed-20220113
