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Multiple neurological effects associated with exposure to organophosphorus pesticides in man
M. Jokanović, P. Oleksak, K. Kuca
Jazyk angličtina Země Irsko
Typ dokumentu časopisecké články, přehledy, práce podpořená grantem
- MeSH
- hyperkinetická porucha * MeSH
- lidé MeSH
- neurotoxické syndromy * etiologie psychologie MeSH
- organofosfáty toxicita MeSH
- organofosforové sloučeniny toxicita MeSH
- pesticidy * toxicita MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
This article reviews available data regarding the possible association of organophosphorus (OP) pesticides with neurological disorders such as dementia, attention deficit hyperactivity disorder, neurodevelopment, autism, cognitive development, Parkinson's disease and chronic organophosphate-induced neuropsychiatric disorder. These effects mainly develop after repeated (chronic) human exposure to low doses of OP. In addition, three well defined neurotoxic effects in humans caused by single doses of OP compounds are discussed. Those effects are the cholinergic syndrome, the intermediate syndrome and organophosphate-induced delayed polyneuropathy. Usually, the poisoning can be avoided by an improved administrative control, limited access to OP pesticides, efficient measures of personal protection and education of OP pesticide applicators and medical staff.
Citace poskytuje Crossref.org
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- $a This article reviews available data regarding the possible association of organophosphorus (OP) pesticides with neurological disorders such as dementia, attention deficit hyperactivity disorder, neurodevelopment, autism, cognitive development, Parkinson's disease and chronic organophosphate-induced neuropsychiatric disorder. These effects mainly develop after repeated (chronic) human exposure to low doses of OP. In addition, three well defined neurotoxic effects in humans caused by single doses of OP compounds are discussed. Those effects are the cholinergic syndrome, the intermediate syndrome and organophosphate-induced delayed polyneuropathy. Usually, the poisoning can be avoided by an improved administrative control, limited access to OP pesticides, efficient measures of personal protection and education of OP pesticide applicators and medical staff.
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- $a Oleksak, Patrik $u Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech republic
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- $a Kuca, Kamil $u Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech republic; Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech republic. Electronic address: kamil.kuca@uhk.cz
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