-
Je něco špatně v tomto záznamu ?
Clinical presentation and pulmonary function tests in post-acute COVID-19 patients
S. Genzor, P. Jakubec, M. Sova, J. Mizera, P. Joppa, R. Burget, P. Pobeha
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články
Free Medical Journals od 1998
Medline Complete (EBSCOhost) od 2007-06-01
ROAD: Directory of Open Access Scholarly Resources od 2001
Odkazy
PubMed
36128850
DOI
10.5507/bp.2022.039
Knihovny.cz E-zdroje
- MeSH
- anosmie MeSH
- COVID-19 * komplikace diagnóza MeSH
- dospělí MeSH
- dyspnoe etiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- prospektivní studie MeSH
- respirační funkční testy MeSH
- SARS-CoV-2 MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
AIMS: The study analysed post-acute COVID-19 symptoms and the pulmonary function test (PFT) results in patients surviving the native strain of the virus. METHODS: The study was prospective; the inclusion criteria were positive PCR test for SARS-CoV-2 and age 18-100. Exclusion criteria were active respiratory infection, known or suspicious pre-existing pulmonary disease, cardiac failure, recent or acute pulmonary embolism, anaemia, and neuromuscular diseases. The recruitment period was 1st March 2020 - 25th December 2020. The initial examination was performed 4-12 weeks after the disease onset. All subjects underwent physical examination, anamnesis, chest x-ray and PFT. RESULTS: The study involved 785 subjects (345 male) mean age 53.8 (SD 14.6). The disease severity groups were: mild (G1), moderate (G2) and severe/critical (G3). Anosmia was present in the acute disease phase in 45.2% of G1 patients, but only in 4.5% of G3 patients. Dyspnoea occurred frequently in more severe groups (40%, 51.8% and 63.7% for G1, G2 and G3 respectively), while cough and fatigue showed no relationship to disease severity. Females were more likely to experience persistent symptoms. PFT results were significantly decreased in more severe groups compared to the mild COVID-19 patients, diffusing capacity was 86.3%, 79% and 68% of predicted values in G1, G2 and G3 respectively. CONCLUSION: Anosmia during the acute phase was associated with mild disease, persisting dyspnoea was more frequent after more severe COVID-19. Females tended to have persisting symptoms in post-acute phase more frequently. PFT results showed decrease with disease severity.
- 000
- 00000naa a2200000 a 4500
- 001
- bmc23008946
- 003
- CZ-PrNML
- 005
- 20230802075202.0
- 007
- ta
- 008
- 230707s2023 xr d f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.5507/bp.2022.039 $2 doi
- 035 __
- $a (PubMed)36128850
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Genzor, Samuel $u Department of Respiratory Diseases and Tuberculosis, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic $7 xx0219019
- 245 10
- $a Clinical presentation and pulmonary function tests in post-acute COVID-19 patients / $c S. Genzor, P. Jakubec, M. Sova, J. Mizera, P. Joppa, R. Burget, P. Pobeha
- 520 9_
- $a AIMS: The study analysed post-acute COVID-19 symptoms and the pulmonary function test (PFT) results in patients surviving the native strain of the virus. METHODS: The study was prospective; the inclusion criteria were positive PCR test for SARS-CoV-2 and age 18-100. Exclusion criteria were active respiratory infection, known or suspicious pre-existing pulmonary disease, cardiac failure, recent or acute pulmonary embolism, anaemia, and neuromuscular diseases. The recruitment period was 1st March 2020 - 25th December 2020. The initial examination was performed 4-12 weeks after the disease onset. All subjects underwent physical examination, anamnesis, chest x-ray and PFT. RESULTS: The study involved 785 subjects (345 male) mean age 53.8 (SD 14.6). The disease severity groups were: mild (G1), moderate (G2) and severe/critical (G3). Anosmia was present in the acute disease phase in 45.2% of G1 patients, but only in 4.5% of G3 patients. Dyspnoea occurred frequently in more severe groups (40%, 51.8% and 63.7% for G1, G2 and G3 respectively), while cough and fatigue showed no relationship to disease severity. Females were more likely to experience persistent symptoms. PFT results were significantly decreased in more severe groups compared to the mild COVID-19 patients, diffusing capacity was 86.3%, 79% and 68% of predicted values in G1, G2 and G3 respectively. CONCLUSION: Anosmia during the acute phase was associated with mild disease, persisting dyspnoea was more frequent after more severe COVID-19. Females tended to have persisting symptoms in post-acute phase more frequently. PFT results showed decrease with disease severity.
- 590 __
- $a
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a mladiství $7 D000293
- 650 _2
- $a mladý dospělý $7 D055815
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 12
- $a COVID-19 $x komplikace $x diagnóza $7 D000086382
- 650 _2
- $a SARS-CoV-2 $7 D000086402
- 650 _2
- $a prospektivní studie $7 D011446
- 650 _2
- $a anosmie $7 D000086582
- 650 _2
- $a respirační funkční testy $7 D012129
- 650 _2
- $a dyspnoe $x etiologie $7 D004417
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Jakubec, Petr, $u Department of Respiratory Diseases and Tuberculosis, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic $d 1971- $7 mzk2007381840
- 700 1_
- $a Sova, Milan, $u Department of Respiratory Diseases and Tuberculosis, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic $u Department of Respiratory Diseases and Tuberculosis, University Hospital Brno and Faculty of Medicine and Dentistry, Masaryk University Brno, Czech Republic $d 1985- $7 xx0140833
- 700 1_
- $a Mizera, Jan $u Department of Respiratory Diseases and Tuberculosis, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic $7 xx0238803
- 700 1_
- $a Joppa, Pavol $u Department of Respiratory Diseases and Tuberculosis, University Hospital and Faculty of Medicine and Dentistry, Pavol Jozef Safarik University, Kosice, Slovak Republic $7 xx0106183
- 700 1_
- $a Burget, Radim $u Department of Telecommunications, University of Technology, Brno, Czech Republic $7 jo2015889385
- 700 1_
- $a Pobeha, Pavol $u Department of Respiratory Diseases and Tuberculosis, University Hospital and Faculty of Medicine and Dentistry, Pavol Jozef Safarik University, Kosice, Slovak Republic $7 xx0171817
- 773 0_
- $w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $x 1804-7521 $g Roč. 167, č. 2 (2023), s. 185-191
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36128850 $y Pubmed
- 910 __
- $a ABA008 $b A 1502 $c 958 $y p $z 0
- 990 __
- $a 20230707 $b ABA008
- 991 __
- $a 20230802075158 $b ABA008
- 999 __
- $a ok $b bmc $g 1964364 $s 1195209
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2023 $b 167 $c 2 $d 185-191 $e 20220906 $i 1804-7521 $m Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic $n Biomed. Pap. Fac. Med. Palacký Univ. Olomouc Czech Repub. (Print) $x MED00012606
- LZP __
- $b NLK198 $a Pubmed-20230707