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Unusual case of inflammatory rhabdomyoblastic tumor in a pediatric patient
L. Krsková, B. Šípalová, J. Balko, S. Zimová, D. Voříšková, P. Brož, R. Kodet, A. Vícha
Pathology, research and practice.
2023 ;
246 (-) :
154524.
[pub] 20230510
Language English Country Germany
Document type Case Reports, Journal Article
Persistent link
https://www.medvik.cz/link/bmc23011167
- MeSH
- Humans MeSH
- Biomarkers, Tumor metabolism MeSH
- Neoplasms * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
Inflammatory rhabdomyoblastic tumor (IRMT) is a rare, recently described skeletal muscle neoplasm of uncertain malignant potential. We report an unusual tumor in the right arm of a 5-year-old boy, which is the first case of a pediatric IRMT. Immunohistochemically, most cells in the tumor were positive for CD163 and CD68 staining. The neoplastic cells themselves showed a skeletal muscle phenotype with a diffuse expression of desmin and a focal expression of myoD1. Mitotic activity was low (1/10 HPF), and no necrosis was observed.
References provided by Crossref.org
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- $a Krsková, Lenka $u Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic. Electronic address: lenka.krskova@lfmotol.cuni.cz
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- $a Inflammatory rhabdomyoblastic tumor (IRMT) is a rare, recently described skeletal muscle neoplasm of uncertain malignant potential. We report an unusual tumor in the right arm of a 5-year-old boy, which is the first case of a pediatric IRMT. Immunohistochemically, most cells in the tumor were positive for CD163 and CD68 staining. The neoplastic cells themselves showed a skeletal muscle phenotype with a diffuse expression of desmin and a focal expression of myoD1. Mitotic activity was low (1/10 HPF), and no necrosis was observed.
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