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The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The IFOS Consensus
JR. Lechien, MF. Vaezi, WW. Chan, JE. Allen, PD. Karkos, S. Saussez, KW. Altman, MR. Amin, T. Ayad, MR. Barillari, PC. Belafsky, JH. Blumin, N. Johnston, F. Bobin, M. Broadhurst, FP. Ceccon, C. Calvo-Henriquez, YG. Eun, CM. Chiesa-Estomba, L....
Language English Country United States
Document type Journal Article
Grant support
IRIS-Recherche Grant (Foundation Roi Baudouin)
Vesale Grant
PubMed
37929860
DOI
10.1002/lary.31134
Knihovny.cz E-resources
- MeSH
- Electric Impedance MeSH
- Laryngopharyngeal Reflux * diagnosis MeSH
- Larynx * MeSH
- Humans MeSH
- Esophageal pH Monitoring MeSH
- Otolaryngologists MeSH
- Surveys and Questionnaires MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
OBJECTIVE: The objective of this work was to gather an international consensus group to propose a global definition and diagnostic approach of laryngopharyngeal reflux (LPR) to guide primary care and specialist physicians in the management of LPR. METHODS: Forty-eight international experts (otolaryngologists, gastroenterologists, surgeons, and physiologists) were included in a modified Delphi process to revise 48 statements about definition, clinical presentation, and diagnostic approaches to LPR. Three voting rounds determined a consensus statement to be acceptable when 80% of experts agreed with a rating of at least 8/10. Votes were anonymous and the analyses of voting rounds were performed by an independent statistician. RESULTS: After the third round, 79.2% of statements (N = 38/48) were approved. LPR was defined as a disease of the upper aerodigestive tract resulting from the direct and/or indirect effects of gastroduodenal content reflux, inducing morphological and/or neurological changes in the upper aerodigestive tract. LPR is associated with recognized non-specific laryngeal and extra-laryngeal symptoms and signs that can be evaluated with validated patient-reported outcome questionnaires and clinical instruments. The hypopharyngeal-esophageal multichannel intraluminal impedance-pH testing can suggest the diagnosis of LPR when there is >1 acid, weakly acid or nonacid hypopharyngeal reflux event in 24 h. CONCLUSION: A global consensus definition for LPR is presented to improve detection and diagnosis of the disease for otolaryngologists, pulmonologists, gastroenterologists, surgeons, and primary care practitioners. The approved statements are offered to improve collaborative research by adopting common and validated diagnostic approaches to LPR. LEVEL OF EVIDENCE: 5 Laryngoscope, 134:1614-1624, 2024.
Abbvie Inc Chicago Illinois USA
Department of Biomedical and Clinical Sciences L Sacco University of Milan Milan Italy
Department of gastroenterology CHU Saint Pierre Brussels
Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan
Department of Laryngology and Broncho Esophagology Mons Belgium
Department of Metrology and Langage Science University of Mons Mons Belgium
Department of Otolaryngology Centre Hospitalier du Luxembourg Luxembourg Luxembourg
Department of Otolaryngology Head and Neck Surgery University of Auckland Auckland New Zealand
Department of Otolaryngology Head Neck Surgery Montreal Hospital Montreal Canada
Department of Otolaryngology New York Medical College School of Medicine Valhalla NY
Department of Otolaryngology School of Medicine São Paulo Federal University Sao Paulo Brazil
Department of Otolaryngology UC Davis Medical Center Sacramento California USA
Department of Otorhinolaryngology and Head and Neck Surgery Polyclinic of Poitiers Poitiers France
Department of Otorhinolaryngology Head and Neck Surgery CHU de Liege Liege Belgium
Department of Surgery Drexel University Philadelphia Pennsylvania USA
Department of Surgery Oncology and Gastroenterology University of Padua Padua Italy
Divisão de Otorrinolaringologia Fleury Medicina e Saúde Laboratórios de Diagnóstico São Paulo Brazil
ENT Centre and Singapore Medical Specialist Centre Singapore Singapore
Faculty of Health Sciences Klaipeda university Klaipeda Lithuania
Institute for Voice and Swallowing Disorders Sleepy Hollow NY USA
References provided by Crossref.org
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- $a Lechien, Jerome R $u Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Brussels, Belgium $u Department of Laryngology and Broncho-Esophagology (Anatomy Department), EpiCURA Hospital, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium $u Department of Otolaryngology-Head and Neck Surgery, Foch Hospital, Paris Saclay University, Research Committee of Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, France $u Department of Otorhinolaryngology and Head and Neck Surgery, Polyclinic of Poitiers, Poitiers, France $1 https://orcid.org/0000000208450845
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- $a The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The IFOS Consensus / $c JR. Lechien, MF. Vaezi, WW. Chan, JE. Allen, PD. Karkos, S. Saussez, KW. Altman, MR. Amin, T. Ayad, MR. Barillari, PC. Belafsky, JH. Blumin, N. Johnston, F. Bobin, M. Broadhurst, FP. Ceccon, C. Calvo-Henriquez, YG. Eun, CM. Chiesa-Estomba, L. Crevier-Buchman, JO. Clarke, G. Dapri, CA. Eckley, C. Finck, PM. Fisichella, AL. Hamdan, S. Hans, K. Huet, R. Imamura, BA. Jobe, T. Hoppo, LP. Maron, V. Muls, AK. O'Rourke, PS. Perazzo, G. Postma, VMN. Prasad, M. Remacle, GD. Sant'Anna, RT. Sataloff, EV. Savarino, A. Schindler, N. Siupsinskiene, PH. Tseng, CH. Zalvan, K. Zelenik, B. Fraysse, JM. Bock, LM. Akst, TL. Carroll
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