-
Je něco špatně v tomto záznamu ?
Synthesis and structural confirmation of selaginpulvilin X
T. Havlíková, S. Nallappan, I. Císařová, L. Rycek
Status neindexováno Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články
PubMed
39415676
DOI
10.1039/d4ob01529k
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
We report the first total synthesis of the natural product selaginpulvilin X, a selaginellaceae polyphenol class of compounds. Our synthetic strategy employs cross-coupling reactions and an organolithium addition to construct the carbon framework. Subsequently, the functional group modifications and deprotection yield the natural product. Spectral analysis confirms the proposed structure by comparing natural and synthetic samples.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc25002097
- 003
- CZ-PrNML
- 005
- 20250123102036.0
- 007
- ta
- 008
- 250117s2024 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1039/d4ob01529k $2 doi
- 035 __
- $a (PubMed)39415676
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Havlíková, Tereza $u Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Prague, Czech Republic. rycekl@natur.cuni.cz $1 https://orcid.org/0000000284216399
- 245 10
- $a Synthesis and structural confirmation of selaginpulvilin X / $c T. Havlíková, S. Nallappan, I. Císařová, L. Rycek
- 520 9_
- $a We report the first total synthesis of the natural product selaginpulvilin X, a selaginellaceae polyphenol class of compounds. Our synthetic strategy employs cross-coupling reactions and an organolithium addition to construct the carbon framework. Subsequently, the functional group modifications and deprotection yield the natural product. Spectral analysis confirms the proposed structure by comparing natural and synthetic samples.
- 590 __
- $a NEINDEXOVÁNO
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Nallappan, Sundaravelu $u Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Prague, Czech Republic. rycekl@natur.cuni.cz
- 700 1_
- $a Císařová, Ivana $u Department of Inorganic Chemistry, Faculty of Science Charles University Hlavova 8, 128 00 Prague, Czech Republic
- 700 1_
- $a Rycek, Lukas $u Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Prague, Czech Republic. rycekl@natur.cuni.cz $1 https://orcid.org/0000000330288829 $7 uk20211110311
- 773 0_
- $w MED00007088 $t Organic & biomolecular chemistry $x 1477-0539 $g Roč. 22, č. 45 (2024), s. 8843-8846
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/39415676 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20250117 $b ABA008
- 991 __
- $a 20250123102030 $b ABA008
- 999 __
- $a ok $b bmc $g 2254472 $s 1238100
- BAS __
- $a 3
- BAS __
- $a PreBMC-PubMed-not-MEDLINE
- BMC __
- $a 2024 $b 22 $c 45 $d 8843-8846 $e 20241121 $i 1477-0539 $m Organic & biomolecular chemistry $n Org Biomol Chem $x MED00007088
- LZP __
- $a Pubmed-20250117