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Monoclonal antibodies reacting with gliadin as tools for assessing antigenic structure responsible for exacerbation of celiac disease
S Stoyanov, H Tlaskalova-Hogenova, P Kocna, H Kristofova, P Fric, WT Hekkens
Immunology letters.
1988 ;
Roč. 17 (č. 4) :
S. 335-338.
Jazyk angličtina Země Nizozemsko
Perzistentní odkaz
https://www.medvik.cz/link/bmc89008357
PubMed
3372012
Knihovny.cz E-zdroje
- MeSH
- antigeny imunologie MeSH
- celiakie * etiologie MeSH
- gliadin imunologie izolace a purifikace škodlivé účinky MeSH
- lidé * MeSH
- monoklonální protilátky imunologie MeSH
- protilátky imunologie MeSH
- rostlinné proteiny * imunologie MeSH
- specificita protilátek * MeSH
- Check Tag
- lidé * MeSH
Monoclonal antibodies reactive with gliadin were prepared by fusion of spleen cells isolated from gliadin-immunized BALB/c mice with myeloma cells. The reactivity of mAbs with different preparations of gliadin and their enzymatic digest were measured using ELISA method. The mAb produced by GL 1 clone was shown to react preferentially with alpha-gliadin and its enzymatic digest.
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