The authors presei.t the case of non-HIV Kaposi's sarcoma treated successfully with Vinblastin (10 mg/m2 at two-week intervals to a total dose of 35 mg/m ), subsequently with interferon α-2b (5 million units s.c. three times per week for 16 weeks). After two years remission a complete relapse of KS occurred. Complete remission occurred again after repeated interferon α-2b treatment 5 million units three times per week for eight weeks, raised to 10 million units three times per week, repeatedly reduced to 5 million units three times per week up to a total 6-month period of administration. From the diagnostic aspect the authors draw attention to the importance of immunohistochemical examination using detection of CD34 antigen on endothelial and perivascular KS cells. In the discussion the authors draw attention to the virus etiology of KS HIV-positive and non-HIV (HHV 8), which explains the successful treatment with interferon α-2b in these conditions.

MFN Klinika dermatovenerológie Martin

Sarcoma idiopathicum multiplex haemorrhagicum Kaposi - case-record of relapse

Sarcoma idiopathicum multiplex haemorrhagicum Kaposi - kazuistika recidívy = Sarcoma idiopathicum multiplex haemorrhagicum Kaposi - case-record of relapse /

Sarcoma idiopathicum multiplex haemorrhagicum Kaposi - case-record of relapse /

Lit: 10

Souhrn: eng