Biology of the chicken MHC (B complex)
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
1358107
Knihovny.cz E-resources
- MeSH
- Blood Group Antigens immunology MeSH
- CD4-Positive T-Lymphocytes immunology MeSH
- Genetic Linkage MeSH
- Haplotypes MeSH
- Histocompatibility Antigens immunology MeSH
- Major Histocompatibility Complex genetics immunology MeSH
- Complement System Proteins genetics MeSH
- Chickens immunology MeSH
- Poultry Diseases immunology MeSH
- Immunity, Innate immunology MeSH
- T-Lymphocytes, Regulatory immunology MeSH
- Genes, Viral genetics MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Blood Group Antigens MeSH
- Histocompatibility Antigens MeSH
- Complement System Proteins MeSH
The major histocompatibility complex (MHC) of chicken is the B complex, originally described as a blood group system. Its three classes of cell membrane antigens have been clearly defined by serological, histogenetic, biochemical, and molecular biological methods. Two of these classes are homologous to classes I and II of mammals (B-F and B-L respectively), while the third--B-G antigen--has not so far been detected in mammals. The possible role of this antigen is discussed. The genes of the MHC play important roles in the regulation of immune response, disease resistance, and regression of Rous sarcomas.
src-specific immunity in inbred chickens bearing v-src DNA- and RSV-induced tumors