Kombinovaná lécba inzulín/gliquidon (Glurenorm) u diabetiku 2. typu po selhání lécbý perorálními antidiabetiky
[Combined therapy with insulin/gliquidone (Glurenorm) in type 2 diabetes after treatment failure using oral antidiabetic agents]

. 1992 Oct ; 38 (10) : 963-7.

Jazyk čeština Země Česko Médium print

Typ dokumentu anglický abstrakt, časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid01481374
Odkazy

PubMed 1481374

The authors evaluate treatment by a combination of insulin and gliquidone (Glurenorm) in 29 type 2 diabetics where long-term treatment with oral antidiabetics alone had failed. Within four months all patients were completely compensated from the metabolic aspect. HbA1c declined from 10.8 to 6.5, C peptide, on the other hand, increased from the original value of 1.2 ng/ml to 1.8 ng/ml. The authors did not observe any undesirable effects or hypoglycaemic states. Gliquidone is suitable for combined treatment because of its short-term effect; stimulation of endogenous secretion has a pulsed character and imitates an intensified regime. The prerequisite of success is a low dose of intermediary insulin to prevent inhibition of the central action of gliquidone.

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