Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74)
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
2968928
Knihovny.cz E-resources
- MeSH
- CD3 Complex immunology MeSH
- Leukosialin MeSH
- Leukocyte Common Antigens MeSH
- Antigens, Neoplasm immunology MeSH
- Cell Line MeSH
- Antigens, CD * MeSH
- Antigens, Differentiation immunology MeSH
- Enzyme-Linked Immunosorbent Assay MeSH
- Histocompatibility Antigens immunology MeSH
- Leukocytes immunology MeSH
- Humans MeSH
- Antibodies, Monoclonal immunology MeSH
- Neprilysin MeSH
- Receptors, Transferrin immunology MeSH
- Sialoglycoproteins * MeSH
- Antibody Specificity MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- CD3 Complex MeSH
- Leukosialin MeSH
- Leukocyte Common Antigens MeSH
- Antigens, Neoplasm MeSH
- Antigens, CD * MeSH
- Antigens, Differentiation MeSH
- Histocompatibility Antigens MeSH
- Antibodies, Monoclonal MeSH
- Neprilysin MeSH
- Receptors, Transferrin MeSH
- Sialoglycoproteins * MeSH
- SPN protein, human MeSH Browser
The specificities of several monoclonal antibodies described by us earlier were determined more exactly: (1) antibodies MEM-31 and MEM-32 are directed against CD8 and CD5 T cell antigens, respectively: (2) MEM-15 and MEM-18 react with the CD14 monocyte antigen; (3) MEM-28 recognizes the CD45 pan-leucocyte antigen. Several new monoclonal antibodies are described: (4) MEM-55 and MEM-58, reactive with subsets of CD45-related molecules; (5) MEM-43, recognizing a broadly expressed 18-kDa glycoprotein; (6) MEM-57, reacting with the CD3 antigen complex: (7) MEM-59 recognizing the CD43 leucocyte antigen; (8) MEM-74, which reacts with an unidentified antigen strongly expressed on several cell lines and many leukaemic cells but absent from most resting leucocytes; (9) MEM-75, directed against transferrin receptor, and (10) MEM-78, recognizing CD10 (CALLA) antigen.
An alternative way of CD4 and CD8 association with protein kinases of the Src family
The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1
Sialic acid-dependent epitopes of CD45 molecules of restricted cellular expression
Human leucocyte surface glycoprotein CDw44 and lymphocyte homing receptor are identical molecules