antigeny CD3 [CD3 Complex]

tematický
53
Termíny

antigen CD3
antigen T3
antigeny T3
CD3 antigen
CD3 antigeny
CD3 komplex
komplex T3

 

Antigens, CD3
CD3 Antigen
CD3 Antigens
T3 Antigen
T3 Antigens
T3 Complex

Perzistentní odkaz   https://www.medvik.cz/link/D017252
Definice

Komplex alespoň pěti membránově vázaných polypeptidů ve zralých T-lymfocytech, které jsou nekovalentně spojeny vzájemně mezi sebou a také s receptorem T-buněk (receptory antigenů T-buněk). CD3 komplex zahrnuje gama, delta, epsilon, zeta a eta řetězce (podjednotky). Když se antigen naváže na receptor T-buněk, komplex CD3 převede aktivační signály do cytoplazmy T-buňky. Gama a delta řetězce (podjednotky) CD3 komplexu jsou oddělené od gama/delta řetězců T-buněčného receptoru (receptory antigenů T-buněk gama-delta).

Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).

DUI
D017252 MeSH Prohlížeč
CUI
M0026174
Předchozí užití
Antigens (1983-1984); Antigens, Differentiation, T-Lymphocyte (1988-1992); Antigens, Surface (1983-1987); Receptors, Antigen, T-Cell (1990-1992)
Historická pozn.
2018 (1993); use T3 ANTIGEN COMPLEX 1983-92; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92
Veřejná pozn.
2018; see ANTIGENS, CD3 1993-2017; CD3 COMPLEX was indexed under RECEPTORS, ANTIGEN, T-CELL 1990-92; under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92; under ANTIGENS, SURFACE 1983-87; and under ANTIGENS 1983-84; for T3 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92

D Chemikálie a léčiva
D23.050 antigeny 1 131
D23.050.301 antigeny povrchové 170
D23.050.301.264 diferenciační antigeny 80
D23.050.301.264.894.080 antigeny CD1 11
D23.050.301.264.894.090 antigeny CD2 11
D23.050.301.264.894.095 antigeny CD3 53
D23.050.301.264.894.095.800 receptory antigenů T-buněk - CD3 komplex 2
D23.050.301.264.894.100 antigeny CD4 84
D23.050.301.264.894.101 antigeny CD5 17
D23.050.301.264.894.107 antigeny CD7 6
D23.050.301.264.894.108 antigeny CD8 47
D23.050.301.264.894.113 antigeny CD13 6
D23.050.301.264.894.118 antigeny CD18 22
D23.050.301.264.894.121 protein genu 3 aktivace lymfocytů 1
D23.050.301.264.894.123 antigeny Thy-1 12
D23.050.301.264.894.127 antigeny CD27 13
D23.050.301.264.894.128 antigeny CD28 16
D23.050.301.264.894.156 antigen CD56 19
D23.050.301.264.894.157 antigeny CD57 7
D23.050.301.264.894.158 antigen CTLA-4 191
D23.050.301.264.894.160 dipeptidylpeptidasa 4 85
D23.050.301.264.894.580 antigeny CD278 1
D23.050.301.264.894.790 antigeny CD279 291
D23.101 biologické markery 5 792
D23.101.100.894.080 antigeny CD1 11
D23.101.100.894.090 antigeny CD2 11
D23.101.100.894.095 antigeny CD3 53
D23.101.100.894.100 antigeny CD4 84
D23.101.100.894.101 antigeny CD5 17
D23.101.100.894.107 antigeny CD7 6
D23.101.100.894.108 antigeny CD8 47
D23.101.100.894.113 antigeny CD13 6
D23.101.100.894.118 antigeny CD18 22
D23.101.100.894.123 antigeny Thy-1 12
D23.101.100.894.127 antigeny CD27 13
D23.101.100.894.128 antigeny CD28 16
D23.101.100.894.156 antigen CD56 19
D23.101.100.894.157 antigeny CD57 7
D23.101.100.894.158 antigen CTLA-4 191
D23.101.100.894.160 dipeptidylpeptidasa 4 85
D23.101.100.894.580 antigeny CD278 1
D23.101.100.894.790 antigeny CD279 291