Ethanol tolerance of Saccharomyces cerevisiae and its relationship to lipid content and composition
Language English Country United States Media print
Document type Journal Article
PubMed
3071514
DOI
10.1007/bf02925769
Knihovny.cz E-resources
- MeSH
- Ethanol pharmacology MeSH
- Lipids biosynthesis pharmacology MeSH
- Fatty Acids metabolism MeSH
- Saccharomyces cerevisiae drug effects metabolism MeSH
- Drug Tolerance MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Ethanol MeSH
- Lipids MeSH
- Fatty Acids MeSH
Saccharomyces cerevisiae strain 14-12 is a highly ethanol-tolerant organism. It can grow in the presence of 13% ethanol but growth is completely prevented at 14% ethanol. A relationship was detected between yeast lipids and ethanol tolerance. A gradual decrease of lipid content was recorded as the concentration of supplemented ethanol increased. Moreover, free fatty acids were comparatively decreased in these lipid extracts. When separately added to media with 14% ethanol different lipids produced varied stimulatory effects on yeast growth. Maximum yield of yeast growth was obtained at 14% ethanol in the presence of lecithin, palmitic acid and cholesterol. Yeast lipids produced in the presence of these fractions are characterized by a relatively high percentage of free fatty acids. The change in the percentage of free fatty acids was shown to be the controlling factor in ethanol tolerance.
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