Variation of antimetabolite sensitivity with different carbon sources in Bacillus subtilis
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, časopisecké články
PubMed
6806159
DOI
10.1007/bf02879762
Knihovny.cz E-zdroje
- MeSH
- arabinosa metabolismus MeSH
- Bacillus subtilis účinky léků metabolismus MeSH
- cystein analogy a deriváty farmakologie MeSH
- ethionin farmakologie MeSH
- glukosa metabolismus MeSH
- glycerol metabolismus MeSH
- hydroxylysin farmakologie MeSH
- maltosa metabolismus MeSH
- mannitol metabolismus MeSH
- metabolismus sacharidů * MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Názvy látek
- arabinosa MeSH
- cystein MeSH
- ethionin MeSH
- glukosa MeSH
- glycerol MeSH
- hydroxylysin MeSH
- maltosa MeSH
- mannitol MeSH
- S-2-aminoethyl cysteine MeSH Prohlížeč
The susceptibility of Bacillus subtilis to amino acid analogues was found to be markedly influenced by the carbon source used in the test media. Thialysine inhibited the bacterium with a greater number of carbon sources than the other two analogues tested. 5-Hydroxylysine was inhibitory with glycerol, lactose, D-xylose, L-arabinose and soluble starch while ethionine showed toxicity with lactose, D-xylose and L-arabinose. None of these analogues were toxic at the levels tested when D-galactose was used as carbon source. The bacterium was not susceptible to thialysine with glycerol, to 5-hydroxylysine with L-arabinose and to ethionine with lactose.
