Critical period in muscle spindle regeneration in grafts of developing rat muscles
Jazyk angličtina Země Německo Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
8651513
DOI
10.1007/bf00184753
Knihovny.cz E-zdroje
- MeSH
- adenosintrifosfatasy metabolismus MeSH
- kosterní svaly růst a vývoj transplantace MeSH
- krysa rodu Rattus MeSH
- myofibrily enzymologie MeSH
- nervosvalová vřeténka anatomie a histologie fyziologie MeSH
- regenerace fyziologie MeSH
- vývoj svalů * MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- adenosintrifosfatasy MeSH
Extensor digitorum longus (EDL) muscles from rats at various intervals after birth were grafted into EDL muscles of adult recipients. Three to twelve months after the operation, host muscles containing the grafts were removed and examined for the presence of muscle spindles in the graft. The aim of the study was to establish when muscle spindles become capable of regeneration during development. Regenerated muscles grafted during the first week after birth were virtually spindleless. Grafts of muscles transplanted 10 and 15 days postnatally contained only 5-8 muscle spindles on average. In contrast, the regenerated grafts originating from muscles of 24- and 28-day-old rats were spindle-rich as in mature muscle grafts; the number of spindles in the transplanted EDL muscles (25.0 +/- 2.3; mean +/- SE) attained values comparable to free standard autografts of these muscles in adult animals. Thus, the critical period after grafting, which also involves the loss of a vascular supply, is considerably longer than the critical period for muscle-spindle survival after nerve injury. Fifteen days after birth, when muscle spindles still survive denervation, only a few regenerated spindles were present in the individual muscle regenerates. We assume that the low resistance of immature spindle capsules to ischaemia accounts for their massive degeneration and abortive spindle regeneration in grafts from 10- to 15-day-old rats.
Zobrazit více v PubMed
Exp Neurol. 1970 Aug;28(2):365-7 PubMed
Cell Tissue Res. 1978 Jan 31;186(3):535-40 PubMed
Acta Neuropathol. 1974;30(2):129-44 PubMed
Acta Neuropathol. 1984;63(1):3-12 PubMed
Dev Biol. 1982 Dec;94(2):265-83 PubMed
Neuroscience. 1983 Nov;10(3):851-9 PubMed
Exp Neurol. 1973 Oct;41(1):214-7 PubMed
Physiol Bohemoslov. 1981;30(6):505-14 PubMed
Neuroscience. 1981;6(1):87-94 PubMed
Rev Can Biol. 1962 Sep-Dec;21:457-70 PubMed
Histochemistry. 1989;92(1):1-13 PubMed
J Neurocytol. 1976 Jun;5(3):319-36 PubMed
J Biophys Biochem Cytol. 1960 Jul;7:725-42 PubMed
Prog Brain Res. 1976;43:59-64 PubMed
Histochemistry. 1976 Apr 21;47(1):43-57 PubMed
J Neurocytol. 1976 Aug;5(4):425-46 PubMed
Sci Prog. 1984 Spring;69(273):45-64 PubMed
Acta Neuropathol. 1974;30(2):109-28 PubMed
Clin Plast Surg. 1979 Jul;6(3):301-16 PubMed
Cell Tissue Res. 1977 Feb 9;177(2):159-80 PubMed
Neurosci Lett. 1989 Feb 13;97(1-2):75-9 PubMed
Physiol Bohemoslov. 1971;20(5):433-9 PubMed
Histochemistry. 1990;94(3):245-56 PubMed
J Biol Chem. 1955 Jun;214(2):839-52 PubMed
Prog Brain Res. 1964;13:175-213 PubMed
J Embryol Exp Morphol. 1961 Sep;9:456-67 PubMed
Cell Tissue Res. 1984;235(3):515-9 PubMed
J Embryol Exp Morphol. 1986 Mar;92:223-54 PubMed
Exp Neurol. 1976 Sep;52(3):421-32 PubMed
