Expression of TNF-alpha in pig fetal cells stimulated in vitro
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
8763156
DOI
10.1007/bf02814750
Knihovny.cz E-resources
- MeSH
- Lymphocyte Activation MeSH
- Macrophage Activation MeSH
- Cell Wall immunology MeSH
- Fetal Blood cytology MeSH
- Gestational Age MeSH
- Liver cytology embryology immunology MeSH
- Cells, Cultured MeSH
- Lipopolysaccharides pharmacology MeSH
- Lymphocytes drug effects metabolism MeSH
- Macrophages drug effects metabolism MeSH
- Swine, Miniature embryology metabolism MeSH
- Mitogens immunology MeSH
- Nocardia chemistry immunology MeSH
- Organic Chemicals MeSH
- Organ Specificity MeSH
- Swine MeSH
- Thymus Gland cytology embryology immunology MeSH
- Tumor Necrosis Factor-alpha biosynthesis MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Lipopolysaccharides MeSH
- Mitogens MeSH
- Nocardia delipidated cell mitogen MeSH Browser
- Organic Chemicals MeSH
- Tumor Necrosis Factor-alpha MeSH
Macrophages and lymphocytes of pig fetuses stimulated in vitro with bacterial mitogens such as lipopolysaccharide and Nocardia opaca delipidated cell mitogen showed a high TNF-alpha cytoplasmic expression. TNF-alpha was detected by immunofluorescence in peripheral blood lymphocytes and lymphocytes from the thymic region as early as at 34 d of gestation. Macrophages were the main producers of TNF-alpha at later developmental stages.
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