Characterization of the limited specificity of antigen recognition in earthworms
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
PubMed
8763159
DOI
10.1007/bf02814753
Knihovny.cz E-zdroje
- MeSH
- adjuvancia imunologická farmakologie MeSH
- epitopy MeSH
- hapteny farmakologie MeSH
- imunizace MeSH
- kyselina arsanilová farmakologie MeSH
- Oligochaeta imunologie MeSH
- proteiny imunologie MeSH
- sérový albumin farmakologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Názvy látek
- adjuvancia imunologická MeSH
- epitopy MeSH
- hapteny MeSH
- kyselina arsanilová MeSH
- proteiny MeSH
- sérový albumin MeSH
Earthworms respond to parenteral stimulation with a protein antigen by the formation of an antigen-binding protein. Earthworms were parenterally stimulated with different proteins and the protein binding was estimated in vitro on both humoral and cellular levels. The binding was significantly higher when the same protein was used for in vivo stimulation. The degree of specificity of the antigen-binding protein after the secondary in vivo challenge increased, but even so it was considerably lower than that of vertebrate immunoglobulins.
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Antimicrobial defense of the earthworm
Characterization of the limited specificity of antigen recognition in earthworms