The germ-free pig model is shown to be useful for studying salmonellosis. The immune status of germ-free and infected gnotobiotic piglets is described. The regulatory role of cytokine is discussed and compared with our experimental findings.

Department of Immunology and Gnotobiology Institute of Microbiology Prague Czech Republic

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Infect Immun. 1997 Dec;65(12):5238-43 PubMed

Z Versuchstierkd. 1982;24(5-6):308-17 PubMed

Infect Immun. 1997 Sep;65(9):3501-8 PubMed

Nature. 1963 Feb 16;197:706 PubMed

Immunol Today. 1997 Feb;18(2):56-8 PubMed

Clin Immunol Immunopathol. 1997 Sep;84(3):244-50 PubMed

Folia Microbiol (Praha). 1997;42(4):403-8 PubMed

Gut. 1996 May;38(5):687-93 PubMed

Physiol Res. 1998;47(5):357-63 PubMed

Immunology. 1996 Aug;88(4):611-7 PubMed

Folia Microbiol (Praha). 1985;30(1):65-75 PubMed

Scand J Immunol. 1981;13(5):467-72 PubMed

Gut. 1996 Dec;39(6):836-45 PubMed

J Exp Med. 1997 Feb 17;185(4):717-30 PubMed

Infect Immun. 1997 Feb;65(2):630-5 PubMed

Adv Exp Med Biol. 1995;371A:463-4 PubMed

J Infect Dis. 1985 Nov;152(5):1050-6 PubMed

Infect Immun. 1997 Dec;65(12):5244-9 PubMed

Infect Immun. 1996 May;64(5):1516-25 PubMed

Vet Immunol Immunopathol. 1997 Jun;57(1-2):105-19 PubMed

Am J Vet Res. 1974 Dec;35(12):1483-9 PubMed

J Immunol. 1990 Aug 15;145(4):1265-9 PubMed

J Exp Med. 1997 Feb 3;185(3):415-27 PubMed

Infect Immun. 1997 Nov;65(11):4509-14 PubMed

Alarmin HMGB1 is released in the small intestine of gnotobiotic piglets infected with enteric pathogens and its level in plasma reflects severity of sepsis

Interference of Bifidobacterium choerinum or Escherichia coli Nissle 1917 with Salmonella Typhimurium in gnotobiotic piglets correlates with cytokine patterns in blood and intestine

Innate immune response in the gut against Salmonella - review

Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium

Cytokines in Salmonella infection