Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
11830949
DOI
10.1007/bf02815626
Knihovny.cz E-resources
- MeSH
- Microscopy, Electron MeSH
- Phagocytosis MeSH
- Germ-Free Life MeSH
- Immunoenzyme Techniques MeSH
- Liver ultrastructure MeSH
- Lymph Nodes metabolism ultrastructure MeSH
- Mesentery MeSH
- Swine, Miniature MeSH
- Nitric Oxide metabolism MeSH
- Lung ultrastructure MeSH
- Swine MeSH
- Salmonella typhimurium pathogenicity MeSH
- Salmonella Infections, Animal immunology metabolism microbiology pathology MeSH
- Intestines ultrastructure MeSH
- Tyrosine analogs & derivatives metabolism MeSH
- Virulence MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- 3-nitrotyrosine MeSH Browser
- Nitric Oxide MeSH
- Tyrosine MeSH
Reactive NO metabolites play a distinct role in the control of Salmonella enterica serovar Typhimurium (ST; a facultative intracellular pathogen) in susceptible host. A significant increase of nitrite and/or nitrate plasma levels, 3-nitro-tyrosine expression and pathological changes in mesenteric lymph nodes have been observed in gnotobiotic piglets orally infected for 1 d with a virulent strain of ST but not in piglets infected with a rough mutant of ST.
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