Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections
Language English Country Germany Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
12635937
DOI
10.1078/1438-4221-00225
PII: S1438-4221(04)70131-9
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Disease Outbreaks * MeSH
- Exfoliatins biosynthesis MeSH
- Genotype MeSH
- Cross Infection epidemiology microbiology MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Polymerase Chain Reaction MeSH
- Hospitals, Maternity * MeSH
- Prophages MeSH
- Blister epidemiology microbiology MeSH
- Electrophoresis, Gel, Pulsed-Field MeSH
- Ribotyping MeSH
- Staphylococcal Scalded Skin Syndrome epidemiology microbiology MeSH
- Staphylococcal Skin Infections epidemiology microbiology MeSH
- Staphylococcus aureus classification genetics metabolism virology MeSH
- Bacterial Typing Techniques * MeSH
- Pregnancy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Exfoliatins MeSH
Genotyping of sixteen exfoliative toxin-producing (ET-positive) strains of Staphylococcus aureus isolated in maternity units of two distant hospitals was accomplished by PFGE, ribotyping, PCR ribotyping, and prophage carriage. Three strains secreted combined ETA + ETB, and the remaining produced ETA and enterotoxin C, or TSST-1. The comparison of various genomic profiles resulted in the identification of nine genotypes. The presence of one prevailing genotype was demonstrated in each hospital. Evidence was given that the outbreak-related ET-positive strains causing the skin disease pemphigus neonatorum disseminated in both the hospitals did not originate from a single source or a common ancestor.
References provided by Crossref.org
Multiplex PCR for detection of three exfoliative toxin serotype genes in Staphylococcus aureus
