• MeSH
• COVID-19 MeSH
• pandemie prevence a kontrola   MeSH
• Světová zdravotnická organizace MeSH
• vakcinace MeSH
• Geografické názvy
• Slovenská republika MeSH

BACKGROUND: Using the perspective of the recent COVID-19 pandemic, which represents a public health challenge that also affects education and the psychological well-being of students, this paper aims to assess the vulnerability to anxiety and stress of the Romanian students from the Faculty of Administration and Business of the University of Bucharest pursuing their degrees in administration and business. METHODS: Our study is based on the results of the survey that was administered to a sample of 422 students (39.6% females and 60.4% males) selected from the pool of 2000 recruited respondents. We employed the ANOVA/linear Dependent Dirichlet Process mixture model to explain the causes of stress and anxiety after various grouping variables represented by gender, specialisation, as well as labour market status. RESULTS: Our results revealed that more than 80% of the students in the sample yielded medium and high vulnerability to stress, while 64% of the respondents were affected by severe anxiety (high frequency of psychological, social, and physical problems that were difficult for them to control). The most important stressors were the fear of getting infected and social distancing, while self-control was considered the most effective coping strategy by 62.6% of employed students. CONCLUSIONS: These results allow us to provide practical recommendations for effectively coping with stress and anxiety among students in Romania and beyond and to help stakeholders and policymakers design strategies for strengthening students' resilience, mental health, and well-being in case of future pandemics or other extreme contexts.

• MeSH
• adaptace psychologická * MeSH
• copingové dovednosti MeSH
• COVID-19 * epidemiologie   psychologie   MeSH
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• pandemie MeSH
• průzkumy a dotazníky MeSH
• psychický stres * epidemiologie   psychologie   MeSH
• SARS-CoV-2 MeSH
• studenti * psychologie   statistika a číselné údaje   MeSH
• univerzity MeSH
• úzkost * epidemiologie   psychologie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Rumunsko MeSH

Scientific evidence regularly guides policy decisions1, with behavioural science increasingly part of this process2. In April 2020, an influential paper3 proposed 19 policy recommendations ('claims') detailing how evidence from behavioural science could contribute to efforts to reduce impacts and end the COVID-19 pandemic. Here we assess 747 pandemic-related research articles that empirically investigated those claims. We report the scale of evidence and whether evidence supports them to indicate applicability for policymaking. Two independent teams, involving 72 reviewers, found evidence for 18 of 19 claims, with both teams finding evidence supporting 16 (89%) of those 18 claims. The strongest evidence supported claims that anticipated culture, polarization and misinformation would be associated with policy effectiveness. Claims suggesting trusted leaders and positive social norms increased adherence to behavioural interventions also had strong empirical support, as did appealing to social consensus or bipartisan agreement. Targeted language in messaging yielded mixed effects and there were no effects for highlighting individual benefits or protecting others. No available evidence existed to assess any distinct differences in effects between using the terms 'physical distancing' and 'social distancing'. Analysis of 463 papers containing data showed generally large samples; 418 involved human participants with a mean of 16,848 (median of 1,699). That statistical power underscored improved suitability of behavioural science research for informing policy decisions. Furthermore, by implementing a standardized approach to evidence selection and synthesis, we amplify broader implications for advancing scientific evidence in policy formulation and prioritization.

• MeSH
• behaviorální vědy * metody   trendy   MeSH
• COVID-19 * epidemiologie   etnologie   prevence a kontrola   MeSH
• komunikace MeSH
• kultura MeSH
• lékařská praxe založená na důkazech * metody   MeSH
• lidé MeSH
• pandemie * prevence a kontrola   MeSH
• sociální normy MeSH
• veřejné zdravotnictví metody   trendy   MeSH
• vůdcovství MeSH
• vytváření politiky * MeSH
• zdravotní politika * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

BACKGROUND: During the COVID-19 pandemic, global healthcare systems faced unprecedented challenges, with a lack of resources and suboptimal patient care emerging as primary concerns. METHODS: Our research, using a comprehensive 24-item electronic questionnaire, "Reflections on the Provision of Healthcare during the COVID-19 Pandemic," delved into the experiences of 938 physicians across the Czech Republic. RESULTS: Over fifty per cent observed a "lower standard of care" compared to pre-pandemic levels. A division arose among physicians regarding a decision's medical, ethical, or legal basis, with a notable gender disparity: male doctors leaned towards medical perspectives, whereas females accented the ethical perspective. Decision-making concerning health care limitations required agreement among the physicians on duty, interdisciplinary teams, or shift supervisors. Physicians reported varying degrees of patient or family participation in health care decisions. Variables such as age, pre-existing health conditions, and life expectancy influenced care decisions. Surprisingly, half of the physicians faced refusals of patients' transportation to better-equipped facilities due to resource constraints. One-third of physicians never discuss the decision about care limitation and other options with patients or their families. As a result, almost fifty per cent of the physicians rarely or never imparted information about care limitations to patients. CONCLUSION: The survey shed light on the profound ethical dilemmas hospital physicians face across different types of healthcare facilities during the pandemic. It uncovered the need for open dialogue and scholarly debate on resource allocation and strengthening the role of patients and their families in care decisions in future healthcare crises.

• MeSH
• COVID-19 * epidemiologie   MeSH
• dospělí MeSH
• klinické rozhodování etika   MeSH
• lékaři * etika   MeSH
• lékařská etika MeSH
• lidé středního věku MeSH
• lidé MeSH
• pandemie MeSH
• postoj zdravotnického personálu MeSH
• průzkumy a dotazníky MeSH
• rozhodování etika   MeSH
• SARS-CoV-2 MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

Patients affected by multiple myeloma (MM) have an increased risk of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection and subsequent coronavirus (20)19 disease (COVID-19)-related death. The changing epidemiological and therapeutic scenarios suggest that there has been an improvement in severity and survival of COVID-19 during the different waves of the pandemic in the general population, but this has not been investigated yet in MM patients. Here we analyzed a large cohort of 1221 patients with MM and confirmed SARS-CoV-2 infection observed between February 2020, and August 2022, in the EPICOVIDEHA registry from 132 centers around the world. Median follow-up was 52 days for the entire cohort and 83 days for survivors. Three-hundred and three patients died (24%) and COVID-19 was the primary reason for death of around 89% of them. Overall survival (OS) was significantly higher in vaccinated patients with both stable and active MM versus unvaccinated, while only a trend favoring vaccinated patients was observed in subjects with responsive MM. Vaccinated patients with at least 2 doses showed a better OS than those with one or no vaccine dose. Overall, according to pandemic waves, mortality rate decreased over time from 34% to 10%. In multivariable analysis, age, renal failure, active disease, hospital, and intensive care unit admission, were independently associated with a higher number of deaths, while a neutrophil count above 0.5 × 109 /L was found to be protective. This data suggests that MM patients remain at risk of SARS-CoV-2 infection even in the vaccination era, but their clinical outcome, in terms of OS, has progressively improved throughout the different viral phases of the pandemic.

• MeSH
• COVID-19 * MeSH
• lidé MeSH
• mnohočetný myelom * terapie   MeSH
• pandemie MeSH
• registrace MeSH
• SARS-CoV-2 MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

OBJECTIVES: Propose a methodology to identify COVID-19 associated deaths using healthcare billing records and evaluate its effectiveness by comparing the results with excess mortality data from 2020 to 2022 and confirmed COVID-19 deaths. METHODS: A retrospective quantitative analysis was conducted by merging healthcare billing records with cause of death data. The term "COVID-19 associated death" was defined as any death occurring within a defined timeframe following a confirmed contact with COVID-19. This category includes individuals who died directly due to COVID-19, with COVID-19 as a contributing factor, or as an aftermath of a COVID-19 infection, as well as those who died from other causes but had previously contracted COVID-19. This broader definition provides a more comprehensive measure of excess mortality compared to the officially confirmed COVID-19 deaths attributed to the virus. RESULTS: We identified 35,399 COVID-19 associated deaths during the 3-year pandemic in Slovakia compared to 21,395 confirmed COVID-19 deaths. CONCLUSION: The identification of COVID-19 associated deaths with our methodology offers a more accurate explanation for the notably high excess mortality observed in Slovakia (31,789 deaths) during the pandemic, relative to the EU27. Given the high level of excess mortality, the officially confirmed deaths are likely underestimated, and the presented methodology provides a more precise measure of mortality. Additionally, healthcare billing records prove valuable in identifying these deaths at the individual patient level using claims data of health insurance companies, which is crucial for implementing targeted preventive measures and improving preparedness for future pandemics.

• MeSH
• COVID-19 * mortalita   MeSH
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• pandemie MeSH
• příčina smrti * MeSH
• retrospektivní studie MeSH
• SARS-CoV-2 MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Slovenská republika MeSH

• MeSH
• COVID-19 * MeSH
• lidé MeSH
• pandemie MeSH
• primární zdravotní péče MeSH
• šíření informací MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• přehledy MeSH
• Geografické názvy
• Česká republika MeSH

Publikace se zaměřuje na epidemické šíření virů a informací a dezinformací. Určeno široké veřejnosti.

• MeSH
• dezinformace MeSH
• epidemie * MeSH
• počítačová simulace MeSH
• přenos infekční nemoci MeSH
• šíření informací MeSH
• sociální chování MeSH
• Publikační typ
• monografie MeSH
• populární práce MeSH

• Konspekt
• Sociální interakce. Sociální komunikace
• NLK Obory
• epidemiologie
• knihovnictví, informační věda a muzeologie
• sociologie

The university student population is particularly vulnerable to depression, which was identified during the COVID-19 pandemic. Understanding how depressive symptoms are interrelated with mental and physical health in students is essential. The aim of this study was to reveal the network of depressive and anxiety symptoms with respect to well-being (life satisfaction, physical health, physical activity, and perceived stress) during a difficult situation-the COVID-19 pandemic-at two measurement points of different pandemic severities. A repeated cross-sectional study was conducted in June 2020 (T1) (lower pandemic severity) and March 2021 (T2) (higher pandemic severity) among 592 and 1230 Czech university students, respectively. The measurements used were the PHQ-9, GAD-7, PSS-10, SWLS, self-rated physical health (SRH), and sociodemographic survey. The network analysis approach was utilized. For the significance of differences, the χ2 test, Student's t test, and ANOVA were performed. The results revealed that scale-level depression, stress, and worse SRH increased over time, whereas life satisfaction decreased. Scale-level anxiety and physical activity were stable over time. PHQ2 Sad mood was the most central and influential node at T1 and T2. PHQ9 Suicidal Ideation was closely related to other variables at T1, whereas PHQ1 Anhedonia was closely related to other variables at T2. The most influential risk factors were the PHQ-2 score and the GAD-2 score, which are associated with uncontrollable worrying, whereas life satisfaction, physical health, and physical activity were the most protective factors. It is crucial to recognize and decrease the PHQ2 score and increase life satisfaction to improve the mental health of university students.

• MeSH
• COVID-19 * psychologie   epidemiologie   MeSH
• cvičení psychologie   MeSH
• deprese * epidemiologie   psychologie   MeSH
• dospělí MeSH
• duševní zdraví MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• osobní uspokojení MeSH
• pandemie MeSH
• průřezové studie MeSH
• průzkumy a dotazníky MeSH
• psychický stres epidemiologie   psychologie   MeSH
• SARS-CoV-2 izolace a purifikace   MeSH
• sebevražedné myšlenky MeSH
• studenti * psychologie   MeSH
• univerzity MeSH
• úzkost * epidemiologie   psychologie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

Systematické šetření epidemie výskytu případů septických onemocnění devíti osob operovaných na operačních sálech nemocnice primárního typu v období od 26. do 28. 11. 2018 bylo zaměřeno na zjištění rozsahu události, vehikula a cesty přenosu nákazy. Komplexní šetření zahrnovalo metody epidemiologické, mikrobiologické, molekulárně biologické a environmentální. Retrospektivní kohortová studie byla uplatněna pro průkaz asociace jednotlivých expozičních faktorů a výsledků, případů septických onemocnění. Z 24 operovaných osob onemocnělo devět (AR 37,5 %). V biologickém materiálu dvou nemocných osob byl nalezen identický kmen Acinetobacter calcoaceticus. Kombinované šetření neodhalilo vehikulum ani cestu přenosu. Okamžitě uplatněná protiepidemická opatření zamezila výskytu dalších případů septických onemocnění.

A systematic investigation of an outbreak of postoperative sepsis in nine patients following surgery in the operating rooms of a primary-type hospital between November 26 and 28, 2018 was conducted to determine the extent of the outbreak, the vehicle, and the route of transmission. The comprehensive investigation included epidemiological, microbiological, molecular biological, and environmental methods. A retrospective cohort study was used to find associations between individual exposure factors and outcomes, the respective septic conditions. Nine of 24 surgery patients were infected (AR 37.5 %). An identical strain of Acinetobacter calcoaceticus was found in biological specimens of two infected patients. The combined investigation did not reveal the vector or route of transmission. Immediate infection prevention and control measures avoided new cases of postoperative sepsis.

• MeSH
• epidemie * prevence a kontrola   MeSH
• epidemiologické metody MeSH
• infekce spojené se zdravotní péčí chirurgie   epidemiologie   MeSH
• klinické laboratorní techniky metody   MeSH
• kontrola infekčních nemocí metody   MeSH
• lidé MeSH
• operační sály MeSH
• pooperační komplikace * chirurgie   epidemiologie   mikrobiologie   MeSH
• přenos infekční nemoci prevence a kontrola   MeSH
• retrospektivní studie MeSH
• sepse * chirurgie   epidemiologie   etiologie   MeSH
• trasování kontaktů metody   MeSH
• Check Tag
• lidé MeSH