Sinonasal tubulopapillary low-grade adenocarcinoma. Histopathological, immunohistochemical and ultrastructural features of poorly recognised entity
Language English Country Germany Media print-electronic
Document type Journal Article
- MeSH
- Adenocarcinoma chemistry pathology surgery MeSH
- Cell Nucleus ultrastructure MeSH
- Adult MeSH
- Microscopy, Electron MeSH
- Immunoenzyme Techniques MeSH
- Middle Aged MeSH
- Humans MeSH
- Microvilli ultrastructure MeSH
- Biomarkers, Tumor analysis MeSH
- Paranasal Sinus Neoplasms chemistry pathology surgery MeSH
- Organelles ultrastructure MeSH
- Adenocarcinoma, Papillary chemistry pathology surgery MeSH
- Aged MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Biomarkers, Tumor MeSH
We present the clinicopathological, histological and immunohistochemical findings of six cases of primary tubulopapillary low-grade adenocarcinoma of the sinonasal tract with ultrastructural examination in one case. Due to its unique features, we believe that primary tubulopapillary low-grade adenocarcinoma of the sinonasal tract represents a tumour entity different from any tumours generally recognised in the sinonasal region. Our cases had an equal sex incidence, with an age range of 44-76 years. The tumour has a tendency to recur, but none of our six patients developed metastases. We feel that it is important to separate this tumour entity from other types of sinonasal adenocarcinomas that exhibit a papillary growth pattern, as they frequently pursue a much more aggressive clinical course than the tumours in this study.
See more in PubMed
Arch Otorhinolaryngol. 1985;241(2):183-93 PubMed
Hum Pathol. 1999 Oct;30(10):1140-5 PubMed
Oral Surg Oral Med Oral Pathol. 1983 Aug;56(2):157-66 PubMed
Cancer. 1973 Jan;31(1):117-29 PubMed
Am J Surg Pathol. 1988 Dec;12(12):946-53 PubMed
Mod Pathol. 2002 Apr;15(4):397-405 PubMed
Am J Surg Pathol. 1996 Aug;20(8):980-94 PubMed
Cancer. 1982 Jul 15;50(2):312-22 PubMed
Am J Surg Pathol. 1986 Mar;10 (3):192-202 PubMed
Am J Otolaryngol. 2002 Sep-Oct;23(5):297-9 PubMed
Cancer. 1983 Aug 1;52(3):542-9 PubMed
Ultrastruct Pathol. 1995 Sep-Oct;19(5):365-70 PubMed
Am J Surg Pathol. 2002 Apr;26(4):458-65 PubMed
Ann Otol Rhinol Laryngol. 1970 Jun;79(3):557-62 PubMed
Am J Surg Pathol. 1991 Apr;15(4):368-75 PubMed
Am J Surg Pathol. 1984 May;8(5):367-74 PubMed
J Laryngol Otol. 1983 Sep;97(9):825-35 PubMed
Development of head and neck pathology in Europe
