Self-reported compliance with osteoporosis medication-qualitative aspects and correlates
Jazyk angličtina Země Irsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
18774663
DOI
10.1016/j.maturitas.2008.07.009
PII: S0378-5122(08)00197-7
Knihovny.cz E-zdroje
- MeSH
- adherence pacienta * MeSH
- inhibitory kostní resorpce terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- postmenopauzální osteoporóza farmakoterapie MeSH
- potravní doplňky MeSH
- průřezové studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- vápník terapeutické užití MeSH
- vitamin D terapeutické užití MeSH
- zdraví - znalosti, postoje, praxe * MeSH
- zdravotnické přehledy MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Názvy látek
- inhibitory kostní resorpce MeSH
- vápník MeSH
- vitamin D MeSH
OBJECTIVES: The analysis aims to assess (1) compliance with anti-osteoporosis pharmacotherapy and (2) the prevalence of calcium and vitamin D co-medication among Czech women in common clinical practice. METHODS: A cross-sectional multicentre questionnaire survey was performed in consecutive secondary care female patients aged > or =40 years. Three main dimensions of compliance were studied: drug compliance (based on missed doses over the last month), co-medication with calcium/vitamin D and compliance with dosing instructions for safe and effective use of bisphosphonates (BIS). RESULTS: The therapy in 200 osteoporosis patients was alendronate (44.5%), risedronate (24.5%), raloxifene (18%) and calcitonin (13%). The three dimensions of compliance were not associated with each other. None of the compliance-related outcomes correlated with the osteoporosis knowledge score obtained in the Osteoporosis Questionnaire (OPQ) of Pande et al. The most frequently reported reason for non-compliance was "drug not handy". Similar mean compliance rates were achieved with once daily and once weekly BIS. The rates of current calcium and vitamin D co-medication were 73% and 62%, respectively. Calcium co-medication was associated with obtaining information on medications against osteoporosis from other sources besides health care professionals (P = 0.038). Compliance with dosing instructions correlated negatively with age (P = 0.001). CONCLUSION: Compliance with osteoporosis medication in Czech women is suboptimal, in particular the prevalence of co-medication with calcium/vitamin D should be higher. It is needed to implement strategies focused on the patient's beliefs about the disease and perceptions of outcome rather than those promoting the knowledge alone.
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