Interictal high-frequency oscillations indicate seizure onset zone in patients with focal cortical dysplasia
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
20362416
DOI
10.1016/j.eplepsyres.2010.03.003
PII: S0920-1211(10)00073-2
Knihovny.cz E-resources
- MeSH
- Analysis of Variance MeSH
- Adult MeSH
- Electrodes MeSH
- Electroencephalography methods MeSH
- Middle Aged MeSH
- Humans MeSH
- Magnetic Resonance Imaging methods MeSH
- Malformations of Cortical Development complications pathology MeSH
- Brain Mapping * MeSH
- Adolescent MeSH
- Brain physiopathology MeSH
- Signal Processing, Computer-Assisted MeSH
- Spectrum Analysis MeSH
- Seizures etiology MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Interictal high-frequency oscillations (HFO) were recently identified in recordings from depth macroelectrodes in epileptic patients. StereoEEG (SEEG) recordings were analyzed in four patients with medically intractable partial seizures due to focal cortical dysplasia type IIA. Characteristics of HFO within seizure onset zone (SOZ), irritative zone, and remote brain areas were investigated. Whilst the rate of occurrence for ripples (80-200 Hz) was significantly higher in recordings from within than outside the SOZ, the rate of fast ripples (200-450 Hz) was less reliable index of SOZ. Interestingly, the mean powers across subjects were significantly higher within than outside the SOZ in both ripple and fast ripple frequency ranges. Our study demonstrates a capacity of interictal HFO to detect the SOZ in focal cortical dysplasias.
References provided by Crossref.org
High frequency oscillations in epileptic and non-epileptic human hippocampus during a cognitive task
Physiological and pathological high frequency oscillations in focal epilepsy
The functional organization of human epileptic hippocampus
