Varicose veins of lower extremities in pregnant women and birth outcomes
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
21033612
DOI
10.21101/cejph.a3596
Knihovny.cz E-resources
- MeSH
- Anticoagulants adverse effects MeSH
- Adult MeSH
- Funnel Chest epidemiology etiology MeSH
- Hydroxyethylrutoside adverse effects analogs & derivatives MeSH
- Pregnancy Complications, Cardiovascular drug therapy epidemiology MeSH
- Humans MeSH
- Logistic Models MeSH
- Infant, Newborn MeSH
- Prospective Studies MeSH
- Retrospective Studies MeSH
- Risk Factors MeSH
- Case-Control Studies MeSH
- Pregnancy MeSH
- Varicose Veins drug therapy epidemiology MeSH
- Congenital Abnormalities epidemiology etiology MeSH
- Pregnancy Outcome * MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Infant, Newborn MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Hungary epidemiology MeSH
- Names of Substances
- Anticoagulants MeSH
- Hydroxyethylrutoside MeSH
- troxerutin MeSH Browser
The objective of the study was to estimate the association of pregnant women with varicose veins of lower extremities (VVLE) and the possible risk for adverse birth outcomes and among them different congenital abnormalities (CAs) in their children. Prospectively and medically recorded VVLE were evaluated in 332 pregnant women who delivered infants with CA (case group) and 566 pregnant women with VVLE who delivered infants without CA (control group) and matched to cases were compared in the population-based data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996. About one-quarter of pregnant women had chronic VVLE while new onset VVLE occurred in the rest of pregnant women. There was no higher risk for adverse birth outcomes of pregnant women with VVLE, in fact the rate of preterm birth and low birth weight was somewhat lower than in the newborns of pregnant women without VVLE. The comparison of VVLE occurrence in pregnant women who had offspring with 21 different CA groups and in pregnant women who later delivered babies without CA showed a higher risk only for pectus excavatum, a mild CA. In conclusion, VVLE in pregnant women does not associate with obvious hazard for their fetuses.
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