A feasibility study comparing pharmacist and physician recommendations for sildenafil treatment
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
PubMed
21324090
DOI
10.1111/j.1743-6109.2011.02212.x
PII: S1743-6095(15)33499-8
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- erektilní dysfunkce farmakoterapie MeSH
- farmaceuti normy statistika a číselné údaje MeSH
- inhibitory fosfodiesterasy 5 aplikace a dávkování terapeutické užití MeSH
- klinické kompetence MeSH
- lékařská praxe - způsoby provádění normy statistika a číselné údaje MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- odborná způsobilost MeSH
- piperaziny aplikace a dávkování terapeutické užití MeSH
- průřezové studie MeSH
- puriny aplikace a dávkování terapeutické užití MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sildenafil citrát MeSH
- sulfony aplikace a dávkování terapeutické užití MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika MeSH
- Německo MeSH
- Španělsko MeSH
- Spojené království MeSH
- Názvy látek
- inhibitory fosfodiesterasy 5 MeSH
- piperaziny MeSH
- puriny MeSH
- sildenafil citrát MeSH
- sulfony MeSH
INTRODUCTION: In Europe, pharmacists may be an important first point of contact for men with erectile dysfunction (ED) asking for advice and treatment. AIM: To determine if European community pharmacists could appropriately recommend suitability for supply of sildenafil 50 mg for the treatment of ED. METHODS: For this cross-sectional, observational study, the current Summary of Product Characteristics was adapted to create a study drug information sheet for use in a pharmacy setting in which, for certain patients, supply is not suitable and referral to a physician is recommended. After training and with use of a guidance questionnaire, pharmacists assessed the suitability of supply of sildenafil 50 mg for men presenting to their pharmacy. Men with self-reported ED who were not currently using a phosphodiesterase type 5 inhibitor were recruited. Within 7 days of the pharmacist-patient interaction, a physician with experience in the management of ED telephoned the subject to assess suitability. If there was discordance between the pharmacist and physician recommendations, the case was independently reassessed by a physician specialist in sexual medicine. MAIN OUTCOME MEASURES: The primary end point was the concordance rate (with 95% confidence intervals) between pharmacist and physician recommendations. Rates were weighted by country sample sizes. RESULTS: Concordance (95% confidence interval) was 0.70 (0.66-0.74) between pharmacist and physician recommendation, indicating agreement in 70% of cases, and was 0.90 (0.86-0.94) between pharmacist and physician specialist in sexual medicine. Furthermore, if the cases in which the pharmacist did not put subjects at risk (i.e., gave an acceptable recommendation) are assessed, the success rate is 83.5% (79.6-87.4%) and 92.8% (90.1-95.5%), respectively. CONCLUSION: Pharmacists were accurate in providing suitable treatment recommendation, generally not recommending sildenafil for men without ED and recommending physician assessment when there was any question about cardiovascular health, other comorbidity, or co-medication.
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