Hyperbaric oxygen therapy in idiopathic sudden sensorineural hearing loss (ISSNHL) in association with combined treatment
Language English Country United States Media print
Document type Journal Article
PubMed
21510273
Knihovny.cz E-resources
- MeSH
- Audiometry MeSH
- Time Factors MeSH
- Adult MeSH
- Glucocorticoids administration & dosage MeSH
- Hyperbaric Oxygenation methods MeSH
- Combined Modality Therapy methods MeSH
- Oxygen blood MeSH
- Middle Aged MeSH
- Humans MeSH
- Methylprednisolone administration & dosage MeSH
- Young Adult MeSH
- Hearing Loss, Sudden etiology therapy MeSH
- Partial Pressure MeSH
- Pentoxifylline administration & dosage MeSH
- Hearing Loss, Sensorineural etiology therapy MeSH
- Retrospective Studies MeSH
- Aged MeSH
- Vasodilation MeSH
- Vasodilator Agents administration & dosage MeSH
- Vinca Alkaloids administration & dosage MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Glucocorticoids MeSH
- Oxygen MeSH
- Methylprednisolone MeSH
- Pentoxifylline MeSH
- Vasodilator Agents MeSH
- Vinca Alkaloids MeSH
- vinpocetine MeSH Browser
The main basic effect of hyperbaric oxygenation (HBO2) on the human body, in our study, was an increased partial pressure of oxygen resulting from an increased amount of oxygen dissolved in plasma. Thus the plasma can become capable of carrying enough oxygen to meet the needs of the body's tissues. From 1 January 2004 to 31 December 2007, a total of 61 patients (62 ears) received medical treatment at the ENT clinic of the 3rd Faculty of Medicine, Charles University, and at the Central Military Hospital in Prague. Treatment consisted of a combination of vasodilatation infusion treatment and HBO2 therapy. The results were evaluated in a retrospective study. The overall percentage of patients showing improvement was 59.7%. However, for those patients who started HBO2 treatment within 10 days of onset, complete recovery, or significant improvement was noted in 65.9%. In contrast, patients who started treatment after 10 days of onset, improvement was noted in only 38.9%. NMR examination revealed that two patients had vestibular schwannoma (also known as acoustic neuroma).