Cancer incidence in Czech black coal miners in association with coalworkers' pneumoconiosis
Jazyk angličtina Země Polsko Médium print-electronic
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
- MeSH
- antrakóza epidemiologie MeSH
- dospělí MeSH
- gastrointestinální nádory epidemiologie MeSH
- incidence MeSH
- kauzalita MeSH
- kohortové studie MeSH
- komorbidita MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory ledvin epidemiologie MeSH
- nádory močového měchýře epidemiologie MeSH
- nádory plic epidemiologie MeSH
- nádory tračníku epidemiologie MeSH
- nádory žaludku epidemiologie MeSH
- nemoci z povolání epidemiologie MeSH
- pracovní expozice statistika a číselné údaje MeSH
- referenční hodnoty MeSH
- senioři MeSH
- těžba uhlí * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
OBJECTIVE: The aim of the study was comparison of cancer incidence risk of lungs, stomach, colon, bladder and kidneys from ex-miners of black coal mines and the general male population of the Czech Republic. MATERIALS AND METHODS: The analysis was conducted in two cohorts of ex-miners according to the presence of coalworkers' pneumoconiosis (CWP). The first cohort included the miners without CWP (N = 6705), and the second cohort included the miners who were compensated for CWP (N = 2158). Personal and occupational data was merged with the data in the National Population Register and the National Oncological Register for the period from 1992 to 2006. Cancer risk in miners in comparison to the general male population of the Czech Republic was evaluated by SIR (Standardized Incidence Ratio) and 95% confidence interval (CI). RESULTS: About twice as high risk of lung cancer was found in miners with CWP (SIR = 2.21; 95% CI: 1.75-2.76). Lung cancer risk correlated with the severity of CWP (simple CWP SIR=1.96; 95% CI: 1.48-2.56, progressive massive fibrosis SIR = 4.29; 95% CI: 2.09-7.87). No increased risk of lung cancer was found in ex-miners without CWP. The risk of malignant neoplasm at the other selected sites was comparable with the risk in the general male population of the Czech Republic. CONCLUSIONS: This study found increased lung cancer risk in coal miners with CWP, but not in those without CWP, comparing with the general population. These results served as the basis for the inclusion of lung cancer in association with CWP into a new Czech list of occupational diseases.
Citace poskytuje Crossref.org
Mortality in Miners with Coal-Workers' Pneumoconiosis in the Czech Republic in the Period 1992-2013
