Lacrimal sac dacryoliths (86 samples): chemical and mineralogic analyses
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články
- MeSH
- aminokyseliny analýza MeSH
- dakryocystorinostomie MeSH
- dítě MeSH
- dospělí MeSH
- ductus nasolacrimalis patologie MeSH
- kaménky chemie ultrastruktura MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- litiáza chemie diagnóza chirurgie MeSH
- mikroanalýza elektronovou sondou MeSH
- mikroskopie elektronová rastrovací MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mukoproteiny analýza MeSH
- nemoci slzného ústrojí diagnóza chirurgie MeSH
- předškolní dítě MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- spektroskopie infračervená s Fourierovou transformací MeSH
- vápník analýza MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- aminokyseliny MeSH
- mukoproteiny MeSH
- vápník MeSH
BACKGROUND: Because dacryoliths occur at low frequency, few studies have focused on their composition. We aimed to present findings from morphological, chemical, and mineralogic analysis of 86 dacryoliths. METHODS: We studied 86 dacryoliths obtained during 832 dacryocystorhinostomies (DCR) performed for postsaccal obstruction. We examined the samples with atomic infrared spectrometry (80 samples), amino acid analysis (17 samples), scanning electron microscopy, and an electron microprobe with an energy dispersive detector (seven samples). RESULTS: Dacryoliths were found in 86/832 DCRs (10.3 %), mostly in patients with primary acquired nasolacrimal duct obstruction. All the dacryoliths were soft, composed of organic material, including proteins and mucoproteins, with approximately 20 % amino acid content. There were no "hard" dacryoliths composed of calcium phosphate. The stones were composed of lobes and lobules built on an amorphous core material with small cavities, probably as a result of various chemical processes that produced a gaseous product. The most frequent elements found in inorganic inclusions were silicon, magnesium, sulfur, potassium, calcium, sodium, and chlorine. Also, some particles had high contents of bismuth, titanium, iron, and organic fibers. The fibers found in the core of dacryoliths suggested a potential origin from cotton swabs used in cosmetics. CONCLUSION: Dacryoliths are composed almost exclusively of organic material, including proteins and mucoproteins, with approximately 20 % amino acid content.
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ClinicalTrials.gov
NCT01826734
