Odours stimulate neuronal activity in the dorsolateral area of the hippocampal formation during path integration
Language English Country Great Britain, England Media electronic-print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24671977
PubMed Central
PMC3996611
DOI
10.1098/rspb.2014.0025
PII: rspb.2014.0025
Knihovny.cz E-resources
- Keywords
- hippocampus, homing, immediate early genes, navigation, olfactory activation, pigeon,
- MeSH
- Olfactory Perception * MeSH
- Columbidae physiology MeSH
- Genetic Markers MeSH
- Hippocampus physiology MeSH
- Odorants * MeSH
- Spatial Navigation MeSH
- Proto-Oncogene Proteins c-fos genetics metabolism MeSH
- Avian Proteins genetics metabolism MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Genetic Markers MeSH
- Proto-Oncogene Proteins c-fos MeSH
- Avian Proteins MeSH
The dorsolateral area of the hippocampal formation of birds is commonly assumed to play a central role in processing information needed for geographical positioning and homing. Previous work has interpreted odour-induced activity in this region as evidence for an 'olfactory map'. Here, we show, using c-Fos expression as a marker, that neuronal activation in the dorsolateral area of the hippocampal formation of pigeons is primarily a response to odour novelty, not to the spatial distribution of odour sources that would be necessary for an olfactory map. Pigeons exposed to odours had significantly more neurons activated in this area of the brain than pigeons exposed to filtered air with odours removed. This increased activity was observed only in response to unfamiliar odours. No change in activity was observed when pigeons were exposed to home odours. These findings are consistent with non-home odours activating non-olfactory components of the pigeon's navigation system. The pattern of neuronal activation in the triangular and dorsomedial areas of the hippocampal formation was, by contrast, consistent with the possibility that odours play a role in providing spatial information.
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