The prediction role of indexes of circulating adipokines for common anthropometric and nutritional characteristics of obesity in the obese Central European population
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24854812
DOI
10.1016/j.eatbeh.2014.03.001
PII: S1471-0153(14)00027-0
Knihovny.cz E-resources
- Keywords
- Adipokine, Correlation, Index, Leptin, Nutrition, Obesity,
- MeSH
- Adipokines blood MeSH
- Adiponectin blood MeSH
- Agouti-Related Protein blood MeSH
- Anthropometry * MeSH
- Biomarkers blood MeSH
- Cytokines blood MeSH
- Diet statistics & numerical data MeSH
- Adult MeSH
- GPI-Linked Proteins blood MeSH
- Complement Factor D analysis MeSH
- Lectins blood MeSH
- Leptin blood MeSH
- Receptors, Leptin blood MeSH
- Middle Aged MeSH
- Humans MeSH
- Nicotinamide Phosphoribosyltransferase blood MeSH
- Nutritional Status * MeSH
- Obesity blood MeSH
- Resistin blood MeSH
- Health Status Indicators * MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Adipokines MeSH
- Adiponectin MeSH
- Agouti-Related Protein MeSH
- Biomarkers MeSH
- Cytokines MeSH
- GPI-Linked Proteins MeSH
- ITLN1 protein, human MeSH Browser
- Complement Factor D MeSH
- Lectins MeSH
- Leptin MeSH
- Receptors, Leptin MeSH
- Nicotinamide Phosphoribosyltransferase MeSH
- Resistin MeSH
AIMS: This study was designed to investigate the relationship between 8 selected adipokines (leptin, leptin receptor, adiponectin, agouti-related peptide, omentin, visfatin, adipsin and resistin), dietary composition and anthropometric parameters found in the Central European obese population. METHODS: A total of 65 unrelated obese Central European Caucasian individuals were recruited for the study. Phenotypic measurements included weight, height, BMI, lean body mass, fat mass, body fat, waist and hip circumference, waist-hip ratio (WHR) and skinfold thickness. Participants completed standardized self-reported 7-day food records. Plasma levels of leptin, leptin receptor, adiponectin, agouti-related peptide (AgRP), resistin, adipsin, omentin and visfatin were examined using ELISA. RESULTS: Multiple associations (weight, height, percentage of body fat, waist circumference, hip circumference, WHR and sum of skinfold thickness) with the circulation levels of the investigated adipokines were identified. Leptin-Leptin receptor (L-LR) levels were found to correlate with total energy intake and macronutrients while adipsin was found to strongly correlate with multiple adipokines. Furthermore, the L-LR index was found to constitute a more accurate description of the relationship between BMI and body weight than individual measurements and the Ag-LR index was found to strongly correlate with both anthropometric and dietary characteristics. CONCLUSION: Following confirmation on larger population samples and on samples of different ethnicities, the reported adipokine indexes could become a useful tool for estimating nutritional status and predicting the body composition of specific patient groups.
References provided by Crossref.org
