Osteoblastic cells trigger gate currents on nanocrystalline diamond transistor

. 2015 May 01 ; 129 () : 95-9. [epub] 20150321

Jazyk angličtina Země Nizozemsko Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid25835144
Odkazy

PubMed 25835144
DOI 10.1016/j.colsurfb.2015.03.035
PII: S0927-7765(15)00169-1
Knihovny.cz E-zdroje

We show the influence of osteoblastic SAOS-2 cells on the transfer characteristics of nanocrystalline diamond solution-gated field-effect transistors (SGFET) prepared on glass substrates. Channels of these fully transparent SGFETs are realized by hydrogen termination of undoped diamond film. After cell cultivation, the transistors exhibit about 100× increased leakage currents (up to 10nA). During and after the cell delamination, the transistors return to original gate currents. We propose a mechanism where this triggering effect is attributed to ions released from adhered cells, which depends on the cell adhesion morphology, and could be used for cell culture monitoring.

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