Quality of life and drug compliance: their interrelationship in rheumatic patients
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26083391
DOI
10.1111/jep.12399
Knihovny.cz E-resources
- Keywords
- adherence, drug compliance, juvenile idiopathic arthritis, quality of life, rheumatic disorders, rheumatoid arthritis, spondyloarthritis, systemic sclerosis,
- MeSH
- Adult MeSH
- Assessment of Medication Adherence * MeSH
- Arthritis, Juvenile drug therapy psychology MeSH
- Quality of Life * MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Disability Evaluation MeSH
- Cross-Sectional Studies MeSH
- Rheumatic Diseases drug therapy psychology MeSH
- Arthritis, Rheumatoid drug therapy psychology MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Spondylarthritis drug therapy psychology MeSH
- Educational Status MeSH
- Severity of Illness Index MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
RATIONALE, AIMS AND OBJECTIVES: In rheumatic disorders, one of the treatment objectives is to improve the patient's quality of life (QoL). Similar to other chronic conditions, drug compliance is poor, but necessary for successful treatment. The relationship between drug compliance and QoL has never been tested. The aim of this study was to elucidate the relationship between drug compliance and QoL in patients with different rheumatic disorders. METHOD: A cross-sectional study was conducted and patients ≥18 years of age with rheumatoid arthritis (RA), spondyloarthritis (SA), juvenile idiopathic arthritis (JIA) and systemic scleroderma (SSc) were recruited. Data were collected by questionnaires including the Short Form 36 version 2, Compliance Questionnaire Rheumatology (CQR), Health Assessment Questionnaire and by a general questionnaire that focused on demographic characteristics. RESULTS: The questionnaires were completed by 289 patients. Of the respondents, 61.6% (178) were treated for RA, 16.3% (47) for SA, 14.2% (41) for SSc and 8% (23) for JIA. The median of CQR score ranged from 66.7 (JIA) to 82.5 (RA), with 51.6% of patients reaching a score <80. QoL was decreased mainly in the physical component, with the lowest rate for patients with SSc. Higher compliance was observed in patients with decreased QoL (physical component), nevertheless, statistical significance of the relationship was reached only in JIA and SA patients. CONCLUSION: Doctors caring for rheumatic patients should focus their efforts on strengthening drug compliance in patients with higher QoL where it seems that lower compliance is more likely.
Department of Clinical Pharmacy Hospital Na Homolce Prague Czech Republic
Hospital Pharmacy Masaryk Hospital Usti nad Labem Czech Republic
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