Quality of life and drug compliance: their interrelationship in rheumatic patients
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
26083391
DOI
10.1111/jep.12399
Knihovny.cz E-zdroje
- Klíčová slova
- adherence, drug compliance, juvenile idiopathic arthritis, quality of life, rheumatic disorders, rheumatoid arthritis, spondyloarthritis, systemic sclerosis,
- MeSH
- dospělí MeSH
- hodnocení adherence k farmakoterapii * MeSH
- juvenilní artritida farmakoterapie psychologie MeSH
- kvalita života * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- posuzování pracovní neschopnosti MeSH
- průřezové studie MeSH
- revmatické nemoci farmakoterapie psychologie MeSH
- revmatoidní artritida farmakoterapie psychologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- spondylartritida farmakoterapie psychologie MeSH
- stupeň vzdělání MeSH
- stupeň závažnosti nemoci MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
RATIONALE, AIMS AND OBJECTIVES: In rheumatic disorders, one of the treatment objectives is to improve the patient's quality of life (QoL). Similar to other chronic conditions, drug compliance is poor, but necessary for successful treatment. The relationship between drug compliance and QoL has never been tested. The aim of this study was to elucidate the relationship between drug compliance and QoL in patients with different rheumatic disorders. METHOD: A cross-sectional study was conducted and patients ≥18 years of age with rheumatoid arthritis (RA), spondyloarthritis (SA), juvenile idiopathic arthritis (JIA) and systemic scleroderma (SSc) were recruited. Data were collected by questionnaires including the Short Form 36 version 2, Compliance Questionnaire Rheumatology (CQR), Health Assessment Questionnaire and by a general questionnaire that focused on demographic characteristics. RESULTS: The questionnaires were completed by 289 patients. Of the respondents, 61.6% (178) were treated for RA, 16.3% (47) for SA, 14.2% (41) for SSc and 8% (23) for JIA. The median of CQR score ranged from 66.7 (JIA) to 82.5 (RA), with 51.6% of patients reaching a score <80. QoL was decreased mainly in the physical component, with the lowest rate for patients with SSc. Higher compliance was observed in patients with decreased QoL (physical component), nevertheless, statistical significance of the relationship was reached only in JIA and SA patients. CONCLUSION: Doctors caring for rheumatic patients should focus their efforts on strengthening drug compliance in patients with higher QoL where it seems that lower compliance is more likely.
Department of Clinical Pharmacy Hospital Na Homolce Prague Czech Republic
Hospital Pharmacy Masaryk Hospital Usti nad Labem Czech Republic
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