Individualized Prophylaxis in Patients with Esophageal Replacement Because of Cancer
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26237191
DOI
10.1089/sur.2014.132
Knihovny.cz E-resources
- MeSH
- Antibiotic Prophylaxis methods MeSH
- Bacteria classification isolation & purification MeSH
- Precision Medicine methods MeSH
- Respiratory Tract Infections prevention & control MeSH
- Middle Aged MeSH
- Humans MeSH
- Esophageal Neoplasms surgery MeSH
- Postoperative Complications prevention & control MeSH
- Preoperative Care methods MeSH
- Sputum microbiology MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
BACKGROUND: Presented are the findings from an analysis of respiratory inflammatory complications in patients undergoing esophageal replacement because of cancer. Respiratory complications are manifested most frequently within five post-operative days, thus, they are likely to be caused by potentially pathogenic micro-organisms originating from the primary or secondary microflora. METHODS: Sputum samples were collected 1-2 wks pre-operatively. In cases of positive microbiologic finding of some potential pathogens, individualized antibiotic prophylaxis was designed. RESULTS: Patients with individualized prophylaxis had fewer respiratory complications (10%) than patients with general antibiotic prophylaxis (41%). CONCLUSIONS: The approach to pre-operative sputum tests should be changed. If culture results are positive for bacteria with high resistance to antimicrobial agents or yeasts, the so-called individualized prophylaxis based on these particular results should be used.
Department of Surgery 1 University Hospital Olomouc Olomouc Czech Republic
Surgical Intensive Care Unit University Hospital Olomouc Olomouc Czech Republic
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