Mining the Chemical Space: Application of 2/4-Nitrobenzenesulfonamides in Solid-Phase Synthesis
ACS combinatorial science.
2015 Oct 12 ;
17 (10) :
570-91.
[epub] 20150914
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
Persistent link
https://www.medvik.cz/link/pmid26325251
- Keywords
- 2-nitrobenzenesulfonyl chloride, 4-nitrobenzenesulfonyl chloride, C-arylation, Fukuyama alkylation, Fukuyama−Mitsunobu alkylation, N-arylation, protective group, rearrangement, solid-phase synthesis,
- MeSH
- Amines chemistry MeSH
- Nitrobenzenes chemical synthesis chemistry MeSH
- Polymers chemistry MeSH
- Sulfonamides chemical synthesis chemistry MeSH
- Combinatorial Chemistry Techniques MeSH
- Solid-Phase Synthesis Techniques methods MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- 4-nitrobenzenesulfonyl chloride MeSH Browser
- Amines MeSH
- Nitrobenzenes MeSH
- Polymers MeSH
- Sulfonamides MeSH
Polymer-supported benzenesulfonamides prepared from various immobilized primary amines and 2/4-nitrobenzenesulfonyl chloride have been used as key intermediates in different chemical transformations, including unusual rearrangements to yield a number of diverse privileged scaffolds. This review summarizes individual strategies in their application to date.
References provided by Crossref.org
Molecules (Basel, Switzerland).
2018 Apr 23 ;
23 (4) :
.
[epub] 20180423
