Body Composition Changes in Adult Females after Lifestyle Intervention Are Influenced by the NYD-SP18 Variant
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26849538
DOI
10.21101/cejph.a4105
Knihovny.cz E-resources
- Keywords
- NYD-SP18, females, intervention, obesity, polymorphism,
- MeSH
- Exercise MeSH
- Adult MeSH
- Genotype MeSH
- Weight Loss genetics MeSH
- Polymorphism, Single Nucleotide genetics MeSH
- Middle Aged MeSH
- Humans MeSH
- Overweight genetics prevention & control MeSH
- Obesity genetics prevention & control MeSH
- GTPase-Activating Proteins genetics MeSH
- Diet, Reducing MeSH
- Aged MeSH
- Body Composition genetics MeSH
- Life Style MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- FAM13A protein, human MeSH Browser
- GTPase-Activating Proteins MeSH
AIM: The study focuses on the analysis of the possible relationship between a common NYD-SP18 (rs6971091, G>A) gene polymorphism and weight loss after lifestyle intervention (combined dietary intake and physical activity) in overweight/obese females. METHODS: We genotyped 139 unrelated non-diabetic Czech females (49.5 ± 13.3 years, average BMI at baseline 32.2 ± 4.6 kg/m². Biochemical and anthropometrical measurements were performed before and after ten weeks of lifestyle intervention. CONCLUSION: Overweight/obese female carriers of the NYD-SP18 rs6971091 GG genotype exhibited a more beneficial response to the intensive lifestyle intervention than others.
Faculty of Public Health and Social Studies South Bohemia University České Budějovice Czech Republic
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