Oesophageal Manometry in Experimental Pigs: Methods and Initial Experience
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26960826
DOI
10.14712/18059694.2016.5
PII: am_2015058040131
Knihovny.cz E-resources
- Keywords
- Experimental pigs, General Anaesthesia, Oesophageal Manometry,
- MeSH
- Anesthesia, General MeSH
- Esophageal Sphincter, Lower physiology MeSH
- Esophagus physiology MeSH
- Manometry methods MeSH
- Models, Animal MeSH
- Sus scrofa * MeSH
- Pressure * MeSH
- Animals MeSH
- Check Tag
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable with healthy human subjects. Evocable swallowing is doable and oesophageal peristalsis is quantifiable. Basic manometric parameters were different in male and female animals. Oesophageal manometry in experimental pigs is feasible. Porcine oesophageal manometry will be usable for preclinical studies in future.
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