PURPOSE: RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation. MATERIALS AND METHODS: The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones. RESULTS: In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential for each of the candidate techniques. CONCLUSIONS: Further work is required before the new methods can be included within the suite of reliable dosimetry methods for use by RENEB partners and others in routine and emergency response scenarios.

b Bundeswehr Institute of Radiobiology Munich Germany

b Laboratorio de Dosimetría Biológica Servicio de Oncología Radioterápica Hospital General Universitario Gregorio Marañón Spain

Bundesamt fuer Strahlenschutz Department Radiation Protection and Health Neuherberg Germany

c Centro de Ciências e Tecnologias Nucleares Instituto Superior Técnico Universidade de Lisboa Bobadela LRS Portugal

c Institutul National De Sanatate Publica Romania

e Institut de Radioprotection et de Sûreté Nucléaire Paris France

e Laboratory of Biosafety and Risk Assessment Division of Health Protection Technologies Casaccia Research Center Italy

f Bundeswehr Institute of Radiobiology affiliated to the University of Ulm Munich Germany

f Leibniz Institute for Farm Animal Biology Dummerstorf Germany

g Istituto Superiore di Sanità Rome Italy

g Università degli Studi di Milano Milano Italy

h Durham University Durham UK

h Stockholm University Stockholm Sweden

i Helmholtz Zentrum München Neuherberg Germany

i Institute of Nuclear Chemistry and Technology Warsaw Poland

j Department of Cell Biology University of Sevilla Spain

k Státní ústav radiační ochrany Prague Czech Republic

l Medical Radiation Physics Lund University Malmö Sweden

m Institut de Recherche Biomédicale des Armées Paris France

o Università degli Studi della Tuscia Italy

p PROCyTOX Commissariat à l'Energie Atomique et aux Energies Alternatives Université Paris Saclay Fontenay aux Roses France

Public Health England Centre for Radiation Chemical and Environmental Hazards Chilton UK

q National Center of Radiobiology and Radiation Protection Bulgaria

r Radiation Protection Centre Vilnius Lithuania

Radiation Protection Service IIS La Fe Health Research Institute Spain

s Laboratory of Health Physics Radiobiology and Cytogenetics Institute of Nuclear and Radiological Sciences and Technology Energy and Safety National Center for Scientific Research Demokritos Greece

Salzburg University Department of Geography and Geology Salzburg Austria

t National Public Health Centre National Research Institute for Radiobiology and Radiohygiene Hungary

u Radiation Biology Unit Forschungszentrum Jülich GmbH Jülich Germany

Universitat Autònoma de Barcelona Spain

v Korea Atomic Energy Research Institute Daejeon South Korea

w Dublin Institute of Technology Dublin Ireland

x Belgian Nuclear Research Centre Mol Belgium

y Ghent University Ghent Belgium

z Oklahoma State University Stillwater USA

Int J Radiat Biol. 2017 Jan;93(1):x. doi: 10.1080/09553002.2016.1246879. PubMed

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