Early detection of pancreatic cancer: impact of high-resolution imaging methods and biomarkers
Language English Country Great Britain, England Media print
Document type Journal Article, Review
PubMed
27769077
DOI
10.1097/meg.0000000000000727
PII: 00042737-201612000-00002
Knihovny.cz E-resources
- MeSH
- Adenoma diagnostic imaging genetics metabolism MeSH
- Biomarkers MeSH
- Early Detection of Cancer methods MeSH
- Cholangiopancreatography, Endoscopic Retrograde MeSH
- Carcinoma, Pancreatic Ductal diagnostic imaging genetics metabolism MeSH
- Elasticity Imaging Techniques MeSH
- Endosonography MeSH
- Carcinoma in Situ diagnostic imaging genetics metabolism MeSH
- Humans MeSH
- Cholangiopancreatography, Magnetic Resonance MeSH
- Magnetic Resonance Imaging MeSH
- MicroRNAs genetics MeSH
- Multidetector Computed Tomography MeSH
- Neoplasms, Cystic, Mucinous, and Serous diagnostic imaging genetics metabolism MeSH
- Pancreatic Neoplasms diagnostic imaging genetics metabolism MeSH
- Positron Emission Tomography Computed Tomography MeSH
- Plectin metabolism MeSH
- Antibodies metabolism MeSH
- Ultrasonography MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Biomarkers MeSH
- DAS-1 protein, human MeSH Browser
- MicroRNAs MeSH
- PLEC protein, human MeSH Browser
- Plectin MeSH
- Antibodies MeSH
High-resolution imaging methods (HRIMs) and biomarkers present the second step of pancreatic cancer (PC) diagnostics in at-risk individuals. These include patients with positive risk factors, early symptoms, nonresponders to the initial antidiabetic therapy, patients older than 50 years of age with new-onset unstable diabetes requiring insulin as well as patients with long-term insulin-non-dependent diabetes and recent (up to 6 months) failure of antidiabetic therapy. The procedures should be started without delay and the co-operation between the primary and tertiary medical centers is highly desirable. An early indication of HRIMs and biomarkers is a prerequisite for the diagnosis of a resectable PC. This publication reviews the recent contribution of HRIMs and biomarkers toward an early diagnosis of PC.
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