Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering.

Department of Biophysics 2nd Faculty of Medicine Charles University Prague 5 Úvalu 84 150 06 Prague 5 Czechia; Institute of Experimental Medicine Academy of Sciences of the Czech Republic v v i Vídeňská 1083 142 20 Prague 4 Czechia; University Centre for Energy Efiicient Buildings Czech Technical University Prague Trinecka 1024 273 43 Bustehrad Czechia

Department of Nonwovens Technical University of Liberec Studentska 2 461 17 Liberec Czechia

Department of Textile Evaluation Technical University of Liberec Studentska 2 461 17 Liberec Czechia

Department of Textile Machine Design Technical University of Liberec Studentska 2 461 17 Liberec Czechia

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