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ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

. 2016 ; 6 () : 47. [epub] 20161230

Status PubMed-not-MEDLINE Language English Country Great Britain, England Media electronic-ecollection

Document type Review, Journal Article

Grant support
G0901530 Medical Research Council - United Kingdom
MR/J000388/1 Medical Research Council - United Kingdom

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and implemented in over 70 countries globally-is now focusing on the implementation of emerging technologies for individualized and predictive medicine. MASK [MACVIA (Contre les Maladies Chroniques pour un Vieillissement Actif)-ARIA Sentinel NetworK] uses mobile technology to develop care pathways for the management of rhinitis and asthma by a multi-disciplinary group and by patients themselves. An app (Android and iOS) is available in 20 countries and 15 languages. It uses a visual analogue scale to assess symptom control and work productivity as well as a clinical decision support system. It is associated with an inter-operable tablet for physicians and other health care professionals. The scaling up strategy uses the recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of the novel ARIA approach is to provide an active and healthy life to rhinitis sufferers, whatever their age, sex or socio-economic status, in order to reduce health and social inequalities incurred by the disease.

1st Department of Family Medicine Medical University of Lodz Lodz Poland

2nd University of Naples and Institute of Translational Medicine Italian National Research Council Naples Italy

Academic Centre of Primary Care University of Aberdeen Aberdeen Scotland UK ; Research in Real Life Cambridge UK

Academic Medical Centre University of Amsterdam Amsterdam The Netherlands

Airway Disease Infection Section National Heart and Lung Institute Imperial College London London UK ; MRC and Asthma UK Centre in Allergic Mechanisms of Asthma London UK

Allergology and Immunology Discipline Luliu Hatieganu University of Medicine and Pharmacy Cluj Napoca Romania

Allergology Department Centre de l'Asthme et des Allergies Hôpital d'Enfants Armand Trousseau Sorbonne Universités UPMC Univ Paris 06 UMR_S 1136 Institut Pierre Louis d'Epidémiologie et de Santé Publique Equipe EPAR 75013 Paris France

Allergy and Asthma Associates of Southern California Mission Viejo CA USA

Allergy and Asthma Medical Group and Research Center San Diego CA USA

Allergy and Clinical Immunology Department Centro Médico Docente La Trinidad and Clínica El Avila Caracas Venezuela

Allergy and Clinical Immunology Department Hospital CUF Descobertas Lisbon Portugal

Allergy and Clinical Immunology Section National Heart and Lung Institute Imperial College London London UK

Allergy and Immunology Division Clinica Ricardo Palma Lima Peru

Allergy and Immunology Laboratory Metropolitan University Simon Bolivar University Barranquilla Colombia ; SLaai Sociedad Latinoamericana de Allergia Asma e Immunologia Cartagena Colombia

Allergy and Respiratory Research Group Centre for Population Health Sciences The University of Edinburgh Medical School Edinburgh UK

Allergy Centre Charité Department of Dermatology and Allergy Charité Universitätsmedizin Berlin Berlin Germany

Allergy Centre Charité Department of Dermatology and Allergy Charité Universitätsmedizin Berlin Berlin Germany ; Global Allergy and Asthma European Network Berlin Germany

Allergy Diagnostic and Clinical Research Unit University of Cape Town Lung Institute Cape Town South Africa

Allergy Unit Complesso Integrato Columbus Rome Italy

Allergy Unit Department of Dermatology University Hospital of Zurich Zurich Switzerland

AQuAS Barcelona Spain ; EUREGHA European Regional and Local Health Association Brussels Belgium

Association Asthme et Allergie Paris France

Asthma and Allergy Clinic Humanitas University Rozzano Milan Italy

Asthma UK Mansell Street London UK

Athens Chest Hospital Athens Greece

Barcelona Institute for Global Health Barcelona Spain

Biomax Informatics AG Munich Germany

Bradford Institute for Health Research Bradford Royal Infirmary Bradford UK

Caisse d'assurance retraite et de la santé au travail du Languedoc Roussillon Montpellier France

Cardio Thoracic and Vascular Department University Hospital of Pisa Pisa Italy

CEDOC Respiratory Research Group Nova Medical School Campo dos Martires da Patria Lisbon Portugal ; Serviço de Imunoalergologia Centro Hospitalar de Lisboa Central EPE Lisbon Portugal

Center for Pediatrics and Child Health Institute of Human Development Royal Manchester Children's Hospital University of Manchester Manchester UK ; Allergy Department 2nd Pediatric Clinic Athens General Children's Hospital P and A Kyriakou University of Athens Athens Greece

Center for Research in Health Technologies and Information Systems CINTESIS Universidade do Porto Porto Portugal ; Allergy Unit Instituto CUF Porto e Hospital CUF Porto Porto Portugal ; Health Information and Decision Sciences Department CIDES Faculdade de Medicina Universidade do Porto Rua Dr Plácido da Costa s n 4200 450 Porto Portugal

Center for Research in Health Technologies and Information Systems CINTESIS Universidade do Porto Porto Portugal ; Allergy Unit Instituto CUF Porto e Hospital CUF Porto Porto Portugal ; Health Information and Decision Sciences Department CIDES Faculdade de Medicina Universidade do Porto Rua Dr Plácido da Costa s n 4200 450 Porto Portugal ; Allergy Unit CUF Porto Hospital and Institute Porto Portugal

Center for Research in Health Technologies and Information Systems CINTESIS Universidade do Porto Porto Portugal ; Allergy Unit Instituto CUF Porto e Hospital CUF Porto Porto Portugal ; Health Information and Decision Sciences Department CIDES Faculdade de Medicina Universidade do Porto Rua Dr Plácido da Costa s n 4200 450 Porto Portugal ; Department of Internal Medicine Centro Hospitalar Sao Joao Porto Portugal

Center for Rhinology and Allergology Wiesbaden Germany

Center for Rhinology and Allergology Wiesbaden Germany ; Department of Otorhinolaryngology Head and Neck Surgery Universitätsmedizin Mannheim Medical Faculty Mannheim Heidelberg University Mannheim Germany

Center of Tuberculosis and Lung Diseases Latvian Association of Allergists Riga Latvia

Centre for Individualized Medicine Department of Pediatrics Faculty of Medicine Linköping University 58185 Linköping Sweden

Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle Ouagadougou Burkina Faso

Centre of Pneumology Coimbra University Hospital Coimbra Portugal

Centre of Pneumology Faculty of Medicine University of Coimbra Coimbra Portugal

Centro Medico Docente La Trinidad Caracas Venezuela

Chachava Clinic David Tvildiani Medical University AIETI Medical School Grigol Robakidze University Tbilisi Georgia

Child Health Queen's University Belfast Northern Ireland UK ; Royal Belfast Hospital for Sick Children Belfast Northern Ireland UK

Children's Hospital Srebrnjak Zagreb Croatia ; School of Medicine University J J Strossmayer Osijek Croatia

Children's Hospital University of Helsinki Helsinki Finland

Clinic of Allergy and Asthma Medical University Sofia Sofia Bulgaria

Clinic of Children's Diseases Faculty of Medicine Vilnius University Vilnius Lithuania ; Public Health Institute Vilnius University Vilnius Lithuania ; European Academy of Paediatrics Brussels Belgium

Clinic of Infectious Chest Diseases Dermatology and Allergology Vilnius University Vilnius Lithuania

Clínica de Alergia Asma y Pediatría Hospital Médica Sur Mexico City Mexico

Clinical Immunology and Allergy Unit Department of Medicine Solna Karolinska Institutet Stockholm Sweden ; Department of Pediatric Pulmonology and Allergy Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden

Clinical Immunology and Allergy Unit Department of Medicine Solna Karolinska Institutet Stockholm Sweden ; Department of Pediatric Pulmonology and Allergy Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden ; University Hospital Stockholm Sweden

Computing Science Department Umeå University Umeå Sweden ; Four Computing Oy Halikko Finland

Conseil Général de l'Economie Ministère de l'Economie de l'Industrie et du Numérique Paris France

Croatian Pulmonary Society Zagreb Croatia

David Hide Asthma and Allergy Research Centre Isle of Wight UK

Département de pédiatrie CHU de Grenoble Grenoble France

Department for Pediatric Pneumology and Immunology Charité Medical University Berlin Germany

Department of Allergy and Clinical Immunology Ajou University School of Medicine Suwon South Korea

Department of Allergy and Immunology Hospital Quirón Bizkaia Erandio Spain

Department of Allergy Immunology and Respiratory Medicine Alfred Hospital and Central Clinical School Monash University Melbourne VIC Australia ; Department of Immunology Monash University Melbourne VIC Australia

Department of Chest Medicine Centre Hospitalier Universitaire UCL Namur Université Catholique de Louvain Yvoir Belgium

Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada

Department of Clinical Immunology Wrocław Medical University Wrocław Poland

Department of Comparative Medicine Messerli Research Institute of the University of Veterinary Medicine Medical University Vienna Austria

Department of Dermatology and Allergy Centre Odense University Hospital Odense Denmark

Department of Dermatology and Allergy Rheinische Friedrich Wilhelms University Bonn Bonn Germany

Department of Dermatology and Allergy Technische Universität München Munich Germany ; ZAUM Center for Allergy and Environment Helmholtz Center Munich Munich Germany

Department of Dermatology Medical University of Graz Graz Austria

Department of ENT Medical University of Graz Graz Austria

Department of Epidemiology CAPHRI School of Public Health and Primary Care Maastricht University Maastricht The Netherlands

Department of Epidemiology Regional Health Service Lazio Region Rome Italy

Department of Geriatrics Getafe University Hospital Madrid Spain

Department of Geriatrics Montpellier University Hospital Montpellier France ; EA 2991 Euromov University Montpellier Montpellier France

Department of Health Social Services and Public Safety Belfast Northern Ireland UK

Department of Immunology and Allergology Faculty of Medicine and Faculty Hospital in Pilsen Charles University Prague Pilsen Czech Republic

Department of Immunology Rheumatology and Allergy and HARC Medical University of Lodz Lodz Poland

Department of Lung Diseases and Clinical Allergology University of Turku Turku Finland ; Allergy Clinic Terveystalo Turku Finland

Department of Medicine and Surgery University of Salerno Baronissi Italy

Department of Medicine Bon Secours Hospital Glasnevin Dublin Ireland

Department of Medicine McMaster University Health Sciences Centre 3V47 1280 Main Street West Hamilton ON Canada

Department of Medicine Nova Southeastern University Davie FL USA

Department of Medicine University of Cape Town Cape Town South Africa

Department of Otolaryngology Head and Neck Surgery Beijing TongRen Hospital Beijing China ; Beijing Institute of Otolaryngology Beijing China

Department of Otolaryngology Nippon Medical School Tokyo Japan

Department of Otolaryngology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

Department of Otorhinolaryngology Academic Medical Centre Amsterdam The Netherlands

Department of Otorhinolaryngology Chiba University Hospital Chiba Japan

Department of Otorhinolaryngology HNO Klinik Universitätsklinikum Düsseldorf Düsseldorf Germany

Department of Paediatrics and Child Health Red Cross Children's Hospital University of Cape Town Cape Town South Africa ; MRC Unit on Child and Adolescent Health University of Cape Town Cape Town South Africa

Department of Paediatrics and Child Health University College Cork Cork Ireland

Department of Paediatrics Maputo Central Hospital Maputo Mozambique

Department of Paediatrics Oslo University Hospital Oslo Norway ; Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway

Department of Paediatrics Oslo University Hospital Oslo Norway ; University of Oslo Oslo Norway

Department of Pathophysiology and Transplantation IRCCS Fondazione Ca'Granda Ospedale Maggiore Policlinico University of Milan Milan Italy

Department of Pediatric Imperial College London London UK

Department of Pediatric Pulmonology and Pediatric Allergology Beatrix Children's Hospital GRIAC Research Institute University Medical Center Groningen University of Groningen Groningen The Netherlands

Department of Pediatrics and Child Health Department of Immunology Faculty of Medicine University of Manitoba Winnipeg MB Canada

Department of Pediatrics Medical School Federal University of Minas Gerais Belo Horizonte Brazil

Department of Pediatrics Nippon Medical School Tokyo Japan

Department of Physiology CHRU PhyMedExp INSERM U1046 CNRS UMR 9214 University Montpellier Montpellier France

Department of Prevention of Environmental Hazards and Allergology Medical University of Warsaw Warsaw Poland

Department of Public Health and Health Products EA 4064 Paris Descartes University Sorbonne Paris Cité Paris France ; Paris Municipal Department of Social Action Childhood and Health Paris France

Department of Public Health and Infectious Diseases Sapienza University of Rome Rome Italy

Department of Public Health and Primary Care Leiden University Medical Center Leiden The Netherlands

Department of Pulmonary Diseases Cerrahpasa Faculty of Medicine Istanbul University Istanbul Turkey

Department of Pulmonary Diseases University Medical Center Groningen University of Groningen Groningen The Netherlands

Department of Pulmonary Medicine CHU Sart Tilman Liege Belgium

Department of Pulmonary Medicine Rashid Hospital Dubai UAE

Department of Pulmonology Celal Bayar University Manisa Turkey

Department of Research Olmsted Medical Center Rochester MN USA

Department of Respiratory Diseases Montpellier University Hospital Montpellier France

Department of Respiratory Diseases Montpellier University Hospital Montpellier France ; EPAR U707 INSERM Paris France ; EPAR UMR S UPMC Paris 6 Paris France

Department of Respiratory Diseases Odense University Hospital Odense Denmark

Department of Respiratory Medicine Academic Medical Center University of Amsterdam Amsterdam The Netherlands

Department of Respiratory Medicine and Allergology University Hospital Lund Sweden

Department of Respiratory Medicine Faculty of Medicine and Dentistry University Hospital Olomouc Olomouc Czech Republic

Department of Respiratory Medicine Ghent University Hospital Ghent Belgium

Department of Respiratory Medicine National Institute of Diseases of the Chest and Hospital Dhaka Bangladesh

Department of Respiratory Medicine University of Bratislava Bratislava Slovakia

Department of Social Medicine Faculty of Medicine University of Crete Heraklion Crete Greece

DIBIMIS University of Palermo Palermo Italy

Division of Allergy and Clinical Immunology University of Salerno Salerno Italy

Division of Allergy Asthma and Clinical Immunology Emek Medical Center Afula Israel

Division of Allergy Clinical Immunology and Rheumatology Department of Pediatrics Federal University of São Paulo São Paulo Brazil

Division of Allergy Department of Pediatric Medicine The Bambino Gesù Children's Research Hospital Holy See Rome Italy

Division of Allergy Immunology University of South Florida Tampa FL USA

Division of Clinical Immunology and Allergy Department of Medicine McMaster University Hamilton ON Canada

Division of Immunodermatology and Allergy Research Department of Dermatology and Allergy Hannover Medical School Hannover Germany

Division of Immunopathology Department of Pathophysiology and Allergy Research Center for Pathophysiology Infectiology and Immunology Medical University of Vienna Vienna Austria

Division of Internal Medicine Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland

Divisions of Allergy and Immunology Department of Internal Medicine and Pediatrics University of Tennessee College of Medicine Germantown TN USA

Ecole des Mines Alès France

Education for Health Warwick UK

EFA European Federation of Allergy and Airways Diseases Patients' Associations Brussels Belgium

EIP on AHA European Innovation Partnership on Active and Healthy Ageing Reference Site Scottish Centre for Telehealth and Telecare NHS 24 Glasgow UK

ENT Department Hospital Clinic Clinical and Experimental Respiratory Immunoallergy IDIBAPS CIBERES Universitat de Barcelona Barcelona Catalonia Spain

ENT Department University Hospital of Kinshasa Kinshasa Congo

EPAR U707 INSERM Paris France

EPAR U707 INSERM Paris France ; EPAR UMR S UPMC Paris 6 Paris France

Eshelman School of Pharmacy University of North Carolina Chapel Hill NC USA

European Union Geriatric Medicine Society Helsinki Finland

Faculdade de Medicina de Lisboa Portuguese National Programme for Respiratory Diseases Lisbon Portugal

Faculty of Medicine Autononous University of Madrid Madrid Spain

Faculty of Medicine University of Belgrade Belgrade Serbia ; Serbian Association for Asthma and COPD Belgrade Serbia

Faculty of the Department of Neurology University of Washington School of Medicine Seattle WA USA

Federico 2 University Hospital Naples Naples Italy

Finnish Lung Association Helsinki Finland

Food Allergy Referral Centre Veneto Region Department of Women and Child Health Padua General University Hospital Padua Italy

GARD Geneva Switzerland

Geriatric Unit Department of Internal Medicine University of Palermo Palermo Italy

Gérontopôle de Toulouse 31059 Toulouse France

Global Allergy and Asthma Platform GAAPP Altgasse 8 10 1130 Vienna Austria

Guy's and St Thomas' NHS Trust Kings College London London UK

Hallym University Sacred Heart Hospital Hallym University College of Medicine Anyang Gyeonggi do South Korea

Hautklinik Klinik für Dermatologie and Allergologie Universitätsklinikum der RWTH Aachen Aachen Germany

Health Economics and Health Technology Assessment Institute of Health and Wellbeing University of Glasgow Glasgow UK

Hospital de Clinicas University of Parana Curitiba Brazil

Hospital de Niños Orlando Alassia Santa Fe Argentina

Hospital of the Hospitaller Brothers in Buda Budapest Hungary

ICVS 3B's PT Government Associate Laboratory Life and Health Sciences Research Institute School of Health Sciences University of Minho Braga Portugal

Immunology and Allergy Division Clinical Hospital University of Chile Santiago Chile

Immunology and Allergy Division Department of Chest Diseases School of Medicine Hacettepe University Ankara Turkey

INSERM U1168 Ageing and Chronic Diseases Epidemiological and Public Health Approaches 94800 Villejuif France

INSERM Université Grenoble Alpes IAB U 1209 Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health Université Joseph Fourier Grenoble France

Institute of Biomedical Imaging and Life Sciences Faculty of Medicine University of Coimbra Coimbra Portugal ; EIP AHA Reference Site Coimbra Portugal

Institute of Epidemiology 1 Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany

Institute of Health Policy and Management IBMG Erasmus University Rotterdam The Netherlands

Institute of Lung Health Respiratory Biomedical Unit University Hospitals of Leicester NHS Trust Leicestershire UK ; Department of Infection Immunity and Inflammation University of Leicester Leicester UK

Institute of Medical Statistics Informatics and Epidemiology Medical Faculty University of Cologne Cologne Germany

Institute of Social Medicine Epidemiology and Health Economics Charité Universitätsmedizin Berlin Berlin Germany ; Institute for Clinical Epidemiology and Biometry University of Wuerzburg Würzburg Germany

IPCRG Aberdeen Scotland UK

iQ4U Consultants Ltd London UK

Julius Center of Health Sciences and Primary Care University Medical Center Utrecht University of Utrecht Utrecht The Netherlands

Karl Landsteiner Institute for Clinical and Experimental Pneumology Hietzing Hospital Vienna Austria

Kronikgune Basque Region Spain

Kyomed Montpellier France

Kyrgyzstan National Centre of Cardiology and Internal Medicine Euro Asian Respiratory Society Bishkek Kyrgyzstan

La Rochelle France

Laboratoire de Pharmacologie Respiratoire UPRES EA220 Hôpital Foch Suresnes Université Versailles Saint Quentin France

Laboratory of Behavioral Immunology Research Division of Clinical Immunology and Allergy The University of Mississippi Medical Center Jackson MS USA

Laboratory of Clinical Immunology Department of Microbiology and Immunology KU Leuven Louvain Belgium

Laboratory of Medical Allergology Allergy Clinic Copenhagen University Hospital at Gentofte Copenhagen Denmark

Laboratory of Molecular Immunology National Research Center Institute of Immunology Federal Medicobiological Agency Moscow Russia

Libra Foundation Buenos Aires Argentina

LungenClinic Grosshansdorf Airway Research Center North German Center for Lung Research Kiel Germany

MACVIA France Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site Montpellier France

MACVIA France Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site Montpellier France ; Caisse d'assurance retraite et de la santé au travail du Languedoc Roussillon Montpellier France

MACVIA France Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site Montpellier France ; Department of Geriatrics Montpellier University Hospital Montpellier France

Medical Commission Montpellier University Hospital Montpellier France

Medical Faculty Vilnius University Vilnius Lithuania

Medical School University of Cyprus Nicosia Cyprus

Medicine Department IRCCS Azienda Ospedaliera Universitaria San Martino Genoa Italy

MedScript Ltd Dundalk County Louth Ireland

Montpellier Région Languedoc Roussillon France

Montpellier University Hospital Montpellier France

Montpellier University Hospital Montpellier France ; Institute of Health Policy and Management IBMG Erasmus University Rotterdam The Netherlands ; Skin and Allergy Hospital Helsinki University Hospital Helsinki Finland

Montpellier University Hospital Montpellier France ; MACVIA France Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site Montpellier France ; INSERM U1168 Ageing and Chronic Diseases Epidemiological and Public Health Approaches 94800 Villejuif France ; CHRU Arnaud de Villeneuve 371 Avenue du Doyen Gaston Giraud 34295 Montpellier Cedex 5 France

Montreal QC Canada

National Center for Disease Control and Public Health of Georgia Tbilisi Georgia

National Center for Research in Chronic Respiratory Diseases Tishreen University School of Medicine Latakia Syria

National eHealth Centre University Hospital Olomouc Olomouc Czech Republic

National Heart and Lung Institute Imperial College London London UK

National Hospital Organization Tokyo National Hospital Tokyo Japan

National Institute of Pneumology M Nasta Bucharest Romania

Neumología y Alergología Infantil Hospital La Fe Valencia Spain

NHS Foundation Trust University Hospitals of Southampton Southampton UK

Northern Health Alliance Newcastle UK

Otolaryngology and Head and Neck Surgery CHU Rangueil Larrey Toulouse France

Pediatric Allergy and Asthma Unit School of Medicine Hacettepe University Ankara Turkey

Pediatric Allergy and Immunology Unit Ain Shams University Cairo Egypt

Pediatric Department University of Verona Hospital Verona Italy

Peercode DV Amsterdam The Netherlands

PELyon Lyon France ; HESPER 7425 Health Services and Performance Resarch Université Claude Bernard Lyon Villeurbanne France

Philippines Society of Allergy Asthma and Immunology Manila Philippines

Pneumology and Allergy Department Hospital Clínic Clinical and Experimental Respiratory Immunoallergy IDIBAPS Barcelona Spain

Polibienestar Research Institute University of Valencia Valencia Spain

Primary Care Respiratory Research Unit Institutode Investigación Sanitaria de Palma IdisPa Palma de Mallorca Spain

ProAR Nucleo de Excelencia em Asma Federal University of Bahia Salvador Brazil

ProAR Nucleo de Excelencia em Asma Federal University of Bahia Salvador Brazil ; GARD Executive Committee Salvador Bahia Brazil

Pulmonary Division Heart Institute Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo São Paulo Brazil

Pulmonary Environmental Epidemiology Unit CNR Institute of Clinical Physiology Pisa Italy ; CNR Institute of Biomedicine and Molecular Immunology A Monroy Palermo Italy

Pulmonary Unit Department of Cardiology Thoracic and Vascular Medicine Arcispedale S Maria Nuova IRCCS Research Hospital Reggio Emilia Italy ; Regional Agency for Health and Social Care Reggio Emilia Italy

Pulmonolory Research Institute FMBA Moscow Russia ; GARD Executive Committee Moscow Russia

Quebec Heart and Lung Institute Laval University Quebec City QC Canada

Queen's University Belfast Northern Ireland UK

Regional Ministry of Health of Andalusia Seville Spain

Regionie Puglia Bari Italy

Respiratory Diseases Department Rangueil Larrey Hospital Toulouse France

Respiratory Medicine Department of Medical Sciences University of Ferrara Ferrara Italy

Royal Brompton Hospital NHS Imperial College London London UK

Royal Brompton Hospital NHS Imperial College London London UK ; National Heart and Lung Institute Imperial College London London UK

S Allergologia S Medicina Interna Hospital Vall d'Hebron Barcelona Spain

Sachs' Children and Youth Hospital Södersjukhuset Stockholm Sweden ; Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden

School of Medicine University CEU San Pablo Madrid Spain

School of Psychology Plymouth University Plymouth UK

Scientific Centre of Children's Health Under the Russian Academy of Medical Sciences Moscow Russia

Scottish Centre for Respiratory Research Cardiovascular and Diabetes Medicine Medical Research Institute Ninewells Hospital University of Dundee Dundee UK

Section of Allergology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands

Section of Allergy and Immunology Saint Louis University School of Medicine Saint Louis MO USA

Section of Otolaryngology Head and Neck Surgery The University of Chicago Medical Center and The Pritzker School of Medicine The University of Chicago Chicago IL USA

Section of Respiratory Disease Department of Oncology Haematology and Respiratory Diseases University of Modena and Reggio Emilia Modena Italy

Service de Physiologie Respiratoire Hôpital Cochin Université Paris Descartes Assistance Publique Hôpitaux de Paris Paris France

Service de Pneumo Allergologie Centre Hospitalo Universitaire de Béni Messous Algers Algeria

Service de Pneumo allergologie Hôpital Saint Joseph Paris France

Service de Pneumologie UMR INSERM UMR1087 and CNR 6291 l'institut du Thorax University of Nantes Nantes France

Serviço de Imunoalergologia Hospital da Luz Lisbon Portugal

Skin and Allergy Hospital Helsinki University Hospital Helsinki Finland

Social Sciences University of Southampton Southampton UK

Sociedad Paraguaya de Alergia Asma e Inmunologıa Asunción Paraguay

Société de Pneumologie de Langue Française Espace francophone de Pneumologie Paris France

Sotiria Hospital Athens Greece

State Key Laboratory of Respiratory Diseases Guangzhou Institute of Respiratory Disease The 1st Affiliated Hospital of Guangzhou Medical University Guangzhou China

Swiss Institute of Allergy and Asthma Research University of Zurich Davos Switzerland

The Allergy and Asthma Institute Lahore Pakistan

The Centre for Allergy Research The Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden

The Queen's Medical Research Institute University of Edinburgh Edinburgh UK

The Royal National TNE Hospital University College London London UK

Tobacco Control Research Centre Iranian Anti Tobacco Association Tehran Iran

Transylvania University Brasov Brasov Romania

Ukrainian Medical Stomatological Academy Poltava Ukraine

Unit of Geriatric Immunoallergology University of Bari Medical School Bari Italy

Universidad Autónoma de Nuevo León San Nicolás de los Garza Mexico

Universidad Católica de Córdoba Córdoba Argentina

Universitätsmedizin der Johannes Gutenberg Universität Mainz Mainz Germany

Université Paris Sud Le Kremlin Bicêtre France ; Service de Pneumologie Hôpital Bicêtre Le Kremlin Bicêtre France ; Inserm UMR_S999 Le Kremlin Bicêtre France

University Clinic of Pulmology and Allergy Medical Faculty Ss Cyril and Methodius University Skopje Republic of Macedonia

University Clinic of Respiratory and Allergic Diseases Golnik Slovenia

University Medical Center Groningen University of Groningen Groningen The Netherlands

University of Medicine and Pharmacy Hochiminh City Vietnam

University of Medicine and Pharmacy Victor Babes Timisoara Romania

University of Southern Denmark Kolding Denmark

University Pneumology Unit AOU Molinette Hospital City of Health and Science of Torino Turin Italy

Upper Airways Research Laboratory ENT Department Ghent University Hospital Ghent Belgium

VIB Inflammation Research Center Ghent University Ghent Belgium

Vienna Challenge Chamber Vienna Austria

Woodbrook Medical Centre Loughborough UK ; Allergy and Respiratory Research Group The University of Edinburgh Edinburgh UK

Woolcock Institute of Medical Research University of Sydney and Sydney Local Health District Glebe NSW Australia

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