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Age-Related Differences in Socio-demographic and Behavioral Determinants of HIV Testing and Counseling in HPTN 043/NIMH Project Accept

. 2018 Feb ; 22 (2) : 569-579.

Language English Country United States Media print

Document type Journal Article, Research Support, N.I.H., Extramural

Grant support
U01 MH066687 NIMH NIH HHS - United States
T32 AI052071 NIAID NIH HHS - United States
P30 MH058107 NIMH NIH HHS - United States
UM1 AI069399 NIAID NIH HHS - United States
UM1 AI069453 NIAID NIH HHS - United States
UM1 AI068619 NIAID NIH HHS - United States
UM1 AI068613 NIAID NIH HHS - United States
UM1 AI068617 NIAID NIH HHS - United States
UM1 AI069423 NIAID NIH HHS - United States
T32 AI007392 NIAID NIH HHS - United States

Links

PubMed 28589504
PubMed Central PMC5718984
DOI 10.1007/s10461-017-1807-5
PII: 10.1007/s10461-017-1807-5
Knihovny.cz E-resources

Youth represent a large proportion of new HIV infections worldwide, yet their utilization of HIV testing and counseling (HTC) remains low. Using the post-intervention, cross-sectional, population-based household survey done in 2011 as part of HPTN 043/NIMH Project Accept, a cluster-randomized trial of community mobilization and mobile HTC in South Africa (Soweto and KwaZulu Natal), Zimbabwe, Tanzania and Thailand, we evaluated age-related differences among socio-demographic and behavioral determinants of HTC in study participants by study arm, site, and gender. A multivariate logistic regression model was developed using complete individual data from 13,755 participants with recent HIV testing (prior 12 months) as the outcome. Youth (18-24 years) was not predictive of recent HTC, except for high-risk youth with multiple concurrent partners, who were less likely (aOR 0.75; 95% CI 0.61-0.92) to have recently been tested than youth reporting a single partner. Importantly, the intervention was successful in reaching men with site specific success ranging from aOR 1.27 (95% CI 1.05-1.53) in South Africa to aOR 2.30 in Thailand (95% CI 1.85-2.84). Finally, across a diverse range of settings, higher education (aOR 1.67; 95% CI 1.42, 1.96), higher socio-economic status (aOR 1.21; 95% CI 1.08-1.36), and marriage (aOR 1.55; 95% CI 1.37-1.75) were all predictive of recent HTC, which did not significantly vary across study arm, site, gender or age category (18-24 vs. 25-32 years).

Los jóvenes representan una gran proporción de nuevas infecciones por el VIH en todo el mundo, sin embargo, su utilización de las pruebas de detección del VIH y el asesoramiento (HTC) sigue siendo baja. Utilizando la encuesta de población transversal de la población realizada en 2011 como parte del proyecto HPTN 043 / NIMH Project Accept, un ensayo aleatorizado por grupos de movilización comunitaria y HTC móvil en Sudáfrica (Soweto y KwaZulu Natal), Zimbabwe, Tanzania y Tailandia, evaluamos las diferencias relacionadas con la edad entre los determinantes sociodemográficos y conductuales de HTC en los participantes del estudio por brazo de estudio, sitio y sexo. Se desarrolló un modelo multivariado de regresión logística utilizando datos individuales completos de 13,755 participantes con pruebas de VIH recientes (antes de 12 meses) como resultado. Los jóvenes (18-24 años) no eran predictivos de HTC recientes, excepto los jóvenes de alto riesgo con múltiples parejas concurrentes, que eran menos probables (aOR 0,75; IC del 95%: 0,61-0,92) compañero. Es importante destacar que la intervención fue exitosa en hombres con éxito específico en el sitio, desde aOR 1,27 (IC 95% 1,05-1,53) en Sudáfrica hasta aOR 2,30 en Tailandia (IC 95%: 1,85-2,84). Por último, en una amplia gama de contextos, la educación superior (aO 1,67; IC del 95%: 1,42; 1,96); mayor estatus socioeconómico (aOR 1,21; IC del 95%: 1,08-1,36) y matrimonio (aOR 1,55; IC del 95%: 1,37 -1.75) eran todos predictivos de HTC recientes, que no variaron significativamente entre brazo de estudio, sitio, sexo o categoría de edad (18-24 vs 25-32 años).

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