Low intrapatient variability of histomorphological findings in periprosthetic tissues from revised metal/ceramic on polyethylene joint arthroplasties
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
29044940
DOI
10.1002/jbm.b.33990
Knihovny.cz E-zdroje
- Klíčová slova
- aseptic loosening, histology, interindividual variability, intraindividual variability, total joint replacement,
- MeSH
- keramika * škodlivé účinky chemie MeSH
- kyčelní protézy * MeSH
- lidé středního věku MeSH
- lidé MeSH
- náhrada kyčelního kloubu * MeSH
- polyethylen * škodlivé účinky chemie MeSH
- protézy - design * MeSH
- retrospektivní studie MeSH
- rozhraní kost/implantát patologie MeSH
- selhání protézy * MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- polyethylen * MeSH
The type of tissue response to implant by-products can be determined by examination of periprosthetic tissues. However, little is known about the most suitable location for tissue sampling. The main goal of this study was to evaluate the extent of variability in tissue response in relation to location of tissue sampling, implant fixation, age and sex in total joint arthroplasties with metal-on-polyethylene or ceramic-on-polyethylene bearing pairs. We processed 236 histology slides from 21 patients and focused on the association between the location of tissue samples and histological features. The presence of the synovial hyperplasia showed a significant association with the particular sampling site. A higher density of high endothelial cell venules was seen in the samples from around the joint, and polyethylene particles were more abundant in noncemented TJA but both findings did not show statistically significant association with the sampling site. The results showed a relatively small variance in the tissue response to prosthetic by-products among tissues sampled from the same patient. Our findings indicate that tissue samples retrieved from similar distance from around the TJA during the revision operation show comparable results of histological analysis. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2008-2018, 2018.
CBG Laboratory a s Ostrava 3 703 00 Czech Republic
Department of Orthopaedic Surgery Stanford Medical Center Outpatient Clinic Redwood City CA 94063
Department of Pathology University Hospital Ostrava Ostrava Poruba 708 52 Czech Republic
Nanotechnology Centre VŠB Technical University of Ostrava Ostrava Poruba 708 33 Czech Republic
Citace poskytuje Crossref.org
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