The optimal bowel preparation intervals before colonoscopy: A randomized study comparing polyethylene glycol and low-volume solutions
Language English Country Netherlands Media print-electronic
Document type Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial
PubMed
29102524
DOI
10.1016/j.dld.2017.10.010
PII: S1590-8658(17)31261-6
Knihovny.cz E-resources
- Keywords
- Ascorbic acid, Bowel preparation, Colonoscopy, Polyethylene glycol, Sodium picosulfate,
- MeSH
- Time Factors MeSH
- Citrates administration & dosage MeSH
- Colonoscopy * MeSH
- Ascorbic Acid administration & dosage MeSH
- Middle Aged MeSH
- Humans MeSH
- Organometallic Compounds administration & dosage MeSH
- Picolines administration & dosage MeSH
- Polyethylene Glycols administration & dosage MeSH
- Preoperative Care methods MeSH
- Cathartics administration & dosage MeSH
- Aged MeSH
- Patient Satisfaction MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Randomized Controlled Trial MeSH
- Comparative Study MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Citrates MeSH
- Ascorbic Acid MeSH
- Organometallic Compounds MeSH
- picosulfate sodium MeSH Browser
- Picolines MeSH
- Polyethylene Glycols MeSH
- Cathartics MeSH
BACKGROUND & AIMS: The optimal duration of bowel preparation has only been assessed for polyethylene glycol (PEG). The aim of the study was to determine the intervals for achieving a satisfactory quality/tolerability of the preparation using PEG/ascorbic acid (PEGA) and sodium picosulphate/magnesium citrate (SPMC), and to compare them with 4L of PEG. METHODS: A randomized, endoscopist-blinded, multicentre study. The 612 outpatients referred to a colonoscopy, were prepared using PEG, SPMC, PEGA. The quality, tolerability, duration of the preparation, and the interval from the end of the preparation to the colonoscopy was assessed. RESULTS: Optimum duration of the preparation was similar for both PEG and SPMC (≥7.3 vs. ≥8.8 h, overall ≥8.4 h). Optimum interval to the colonoscopy was ≤11.8 h and did not differ between preparations (PEG, PEGA ≤ 11.8, SPMC ≤ 13.3 h). These times were the only predictors for a satisfactory preparation. The tolerability depends on the product type (SPMC) only. Timing of the preparation or the other factors had no impact on tolerability. CONCLUSION: The optimum intervals for bowel preparation are identical for all preparations. Satisfactory preparation is achived at the preparation length ≥8.4 h and the time to colonoscopy ≤11.8 h.
References provided by Crossref.org
