Adherence k léčbě non-vitamin K perorálními antikoagulancii u nevalvulární fibrilace síní: přehled literatury
[Medication adherence to non-vitamin K antagonist oral anticoagulants at non-valvular atrial fibrillation - the literature review]
Language Czech Country Czech Republic Media print
Document type Journal Article, Review
PubMed
29127745
PII: 62131
- MeSH
- Anticoagulants therapeutic use MeSH
- Administration, Oral MeSH
- Atrial Fibrillation drug therapy MeSH
- Assessment of Medication Adherence * MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Anticoagulants MeSH
Medication adherence is a complex problem reflecting variations in terms of medication taking behavior. It is essential in maximizing of the effect and risk minimization of the therapy and health care costs reduction, even in the case of oral anticoagulants (non-vitamin K antagonist oral anticoagulants - NOACs). The aim of this paper was to review the published literature and to discuss results in the field of medication adherence to NOACs in patients with non-valvular atrial fibrillation (NVAF). Based on the searching in databases Embase and PubMed 25 studies were identified, of which conclusions were summarized in this paper. Patients treated with dabigatran reported poorer medication adherence than patients with rivaroxaban. However, medication adherence is influenced by many circumstances as well as included studies were not sufficiently uniform, therefore, a prerequisite for further investigation of this issue is expected.Key words: apixaban - atrial fibrillation - dabigatran - medication adherence - patient compliance - rivaroxaban.
Electronic Monitoring of Medication Adherence to Direct Oral Anticoagulants: A Systematic Review
Patterns in anticoagulant utilization in the Czech Republic during 2007-2017